Can an antibiotic helper drug help smokers quit?
NCT ID NCT03713424
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 34 times
Summary
This study tests whether clavulanic acid, a drug used to boost antibiotics, can help people smoke less. Thirty adult smokers will take either the drug or a placebo for several weeks. Researchers will measure smoking levels and use brain scans to see if the drug changes how the brain responds to smoking-related images.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Missouri - Columbia
RECRUITINGColumbia, Missouri, 65211, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Clavulanic Acid
What this could lead to
If it works, this could point toward a new treatment to help people quit smoking by reducing cravings.
What could go wrong
This is a small, early-phase trial with only 30 participants. It may not show a clear benefit, and results may not apply to all smokers.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.