Financial incentives and counseling aim to help homeless veterans quit smoking
NCT ID NCT07714200
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This study tests a program called Abstinence Reinforcement Therapy (ART+) to help veterans who are homeless quit smoking. The program combines telehealth counseling, nicotine replacement therapy, and financial rewards for staying smoke-free. Researchers will compare ART+ to standard smoking cessation care in 120 veterans, using saliva tests to verify abstinence.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a combination of cognitive behavioral therapy, nicotine replacement therapy, bupropion, and mobile contingency management (financial incentives for abstinence)
- What this could lead to
- If successful, this approach could provide an effective, scalable way to help homeless veterans quit smoking, reducing smoking-related deaths in this high-risk group.
- What could go wrong
- The trial is relatively small (120 participants) and relies on self-report plus biochemical verification, which may not capture long-term success. Financial incentives may not be sustainable outside a research setting.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Mar 2027
An estimate. Start dates often move.
- Expected to finish
-
Sep 2030
An estimate. End dates often move.
- Lead sponsor
-
A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Are homeless * Smoke at least 5 cigarettes daily with CO indicating current smoking at time of screening assessment * Are willing to try to quit smoking in next 30 days Exclusion Criteria: * Have uncontrolled psychotic symptoms * Have active substance dependence other than nicotine (participants in partial remission with at least one month sobriety will be included) * Have severely impaired hearing or speech
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Tobacco use disorder are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Durham VA Medical Center, Durham, NC
Durham, North Carolina, 27705-3875, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a health Worker's support break the smoking habit in mental illness?
- Virtual reality could help new moms kick the habit
- Magnetic pulses aimed at the brain might help smokers with opioid addiction kick the habit
- Personalized nicotine patch dosing may boost quit rates
- A stronger nicotine patch might break the dual Smoking-Vaping habit
- Could a child's doctor visit spark a parent's quit-smoking journey?