Scientists test synthetic nicotine and new Nicotine-Like chemicals in vapers

NCT ID NCT07348224

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will compare how synthetic nicotine and a nicotine analogue (6-methylnicotine) behave in the body versus traditional tobacco-derived nicotine. Twenty-four regular vapers will vape e-liquids containing these substances, and researchers will measure their levels in the blood and their effects. The goal is to understand if these newer products work the same way as standard nicotine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

synthetic nicotine (S-nicotine, racemic nicotine) and nicotine analogue 6-methylnicotine

What this could lead to

If successful, this could clarify whether synthetic nicotine and nicotine analogues work like traditional nicotine, informing regulation and product safety.

What could go wrong

This is a small, early-phase study (24 people) that only measures short-term effects. Results may not apply to long-term use or broader populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nicotine dependence Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Inselspital

    Bern, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••