NICOTINE
Clinical trials for NICOTINE explained in plain language.
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New study offers e-cigarettes and quit-smoking pill to 6,000 hard-to-treat smokers
Disease control Not yet recruitingThis study looks at whether e-cigarettes or a medicine called cytisine can help people who still smoke at least 5 cigarettes a day even after trying nicotine patches, gum, or counseling. Over 4 years, 6,000 participants will be randomly given either an e-cigarette starter kit or …
Matched conditions: NICOTINE
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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Sleep drug may help smokers stay Smoke-Free
Symptom relief Not yet recruitingThis study tests whether daridorexant, a recently FDA-approved insomnia drug, can improve sleep quality and daytime alertness in smokers who are trying to quit. Poor sleep is a major reason people relapse during a quit attempt. The study will enroll 44 adult smokers who smoke at …
Matched conditions: NICOTINE
Phase: PHASE4 • Sponsor: Legacy Health System • Aim: Symptom relief
Last updated May 11, 2026 20:50 UTC
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Synthetic nicotine under the microscope: new study aims to uncover its true effects
Knowledge-focused Not yet recruitingThis study will compare the effects of synthetic nicotine and nicotine analogues to traditional tobacco-derived nicotine in 24 adults who regularly vape. Researchers will measure how much of these substances get into the blood and how the body processes them. The goal is to bette…
Matched conditions: NICOTINE
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated May 17, 2026 12:55 UTC