NICOTINE
Clinical trials for NICOTINE explained in plain language.
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Could better sleep be the key to quitting cigarettes?
Disease control Not yet recruitingThis study is testing whether a prescription sleep medicine called daridorexant can help people quit smoking. Researchers want to see if improving sleep quality and daytime alertness during the first three weeks of quitting makes it easier to stay smoke-free. The study will invol…
Matched conditions: NICOTINE
Phase: PHASE4 • Sponsor: Legacy Health System • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New hope for stubborn smokers: major trial tests two alternative quitting aids
Disease control Not yet recruitingThis study is testing whether e-cigarettes or a medication called cytisine can help people who continue to smoke despite trying standard treatments like nicotine patches and counseling. It will involve 6,000 adults in Ontario who smoke at least 5 cigarettes daily and have not qui…
Matched conditions: NICOTINE
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Scientists probe: is Lab-Made nicotine different?
Knowledge-focused Not yet recruitingThis study aims to understand how the body processes and reacts to synthetic nicotine and nicotine-like chemicals from e-cigarettes, compared to regular tobacco nicotine. It will involve 24 adults who currently use e-cigarettes. Participants will use different e-cigarette product…
Matched conditions: NICOTINE
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC