NICOTINE
Clinical trials for NICOTINE explained in plain language.
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New hope for hardcore smokers: E-Cigs and natural pills put to the test
Disease control Not yet recruitingThis study will test whether e-cigarettes or a natural supplement called cytisine can help people who smoke at least 5 cigarettes a day and haven't been able to quit with standard treatments like nicotine patches or counseling. Over 4 years, 6,000 participants will be randomly as…
Matched conditions: NICOTINE
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Can a sleep pill help smokers kick the habit?
Symptom relief Not yet recruitingThis study tests whether daridorexant, a recently FDA-approved sleep medication, can improve sleep quality and daytime alertness in smokers who struggle with insomnia during quit attempts. About 44 adult smokers who smoke at least 10 cigarettes daily will take the drug or a place…
Matched conditions: NICOTINE
Phase: PHASE4 • Sponsor: Legacy Health System • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Scientists test synthetic nicotine and new Nicotine-Like chemicals in vapers
Knowledge-focused Not yet recruitingThis study will compare how synthetic nicotine and a nicotine analogue (6-methylnicotine) behave in the body versus traditional tobacco-derived nicotine. Twenty-four regular vapers will vape e-liquids containing these substances, and researchers will measure their levels in the b…
Matched conditions: NICOTINE
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC