Can a sleep pill help smokers kick the habit?
NCT ID NCT07328594
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether daridorexant, a recently FDA-approved sleep medication, can improve sleep quality and daytime alertness in smokers who struggle with insomnia during quit attempts. About 44 adult smokers who smoke at least 10 cigarettes daily will take the drug or a placebo for 3 weeks while trying to reduce or stop smoking. Researchers will monitor sleep patterns, alertness, and withdrawal symptoms to see if better sleep helps with quitting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
daridorexant
What this could lead to
If successful, daridorexant could help smokers with insomnia sleep better and stay alert during quit attempts, potentially improving cessation rates.
What could go wrong
This is a small, early-phase trial with only 44 participants, so results may not apply widely. The drug may not improve smoking abstinence or could cause side effects like daytime drowsiness.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Legacy Research Institute
Portland, Oregon, 97232, United States