Can a sleep pill help smokers kick the habit?
NCT ID NCT07328594
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether daridorexant, a recently FDA-approved sleep medication, can improve sleep quality and daytime alertness in smokers who struggle with insomnia during quit attempts. About 44 adult smokers who smoke at least 10 cigarettes daily will take the drug or a placebo for 3 weeks while trying to reduce or stop smoking. Researchers will monitor sleep patterns, alertness, and withdrawal symptoms to see if better sleep helps with quitting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- daridorexant
- What this could lead to
- If successful, daridorexant could help smokers with insomnia sleep better and stay alert during quit attempts, potentially improving cessation rates.
- What could go wrong
- This is a small, early-phase trial with only 44 participants, so results may not apply widely. The drug may not improve smoking abstinence or could cause side effects like daytime drowsiness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Legacy Research Institute
Portland, Oregon, 97232, United States
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