SLEEP

This study tests a 24-week program called Black Impact to improve heart health and reduce stress in Black men. About 340 Black men with below-ideal heart health will either join the program right away or be placed on a waitlist. The program includes weekly exercise, health educat…

This study is testing whether wearable devices like movement sensors, EEG headbands, and smartphones can accurately measure sleep stages compared to the standard sleep test (polysomnography). It involves 96 healthy volunteers and people with sleep problems. The goal is to see if …

This study checks if wearable devices like movement sensors, headbands, and pulse oximeters can accurately track sleep stages in children and teens aged 3 to 18. Results will be compared with standard sleep tests (polysomnography) to see if these gadgets can help diagnose sleep p…

This study tests whether the sleep aid suvorexant can slow the buildup of a protein called amyloid in the brain, which is linked to Alzheimer's disease. About 200 healthy adults aged 65 and older will take either the drug or a placebo for a period of time. Researchers will measur…

This study tests whether taking a collagen supplement for 8 days can improve quality of life, appetite, mood, and blood sugar control in overweight or obese adults aged 18-65. Participants will take the supplement or a placebo, fill out questionnaires, and wear a continuous gluco…

This study tests whether adding bright light therapy, methylphenidate, or melatonin to cognitive behavior therapy (CBT) can improve sleep and related symptoms like fatigue, anxiety, and depression in 188 adults with advanced cancer. Participants must have poor sleep for at least …

This study tests two parent-led programs for children ages 3-5 who have early signs of ADHD and trouble sleeping. One program focuses on general behavior strategies, while the other adds sleep-focused techniques. Researchers want to see if the sleep-focused approach is more helpf…

This study tests whether daily morning bright light therapy can improve sleep, brain health, and recovery in 105 adults with opioid use disorder who are already on medication like methadone or buprenorphine. Participants will be randomly assigned to receive either bright or dim l…

This study tests whether a special type of lighting that changes throughout the day can improve sleep, body clock function, and overall well-being in frail adults over 65 who are staying in the hospital. Researchers will measure changes in melatonin levels and sleep patterns. The…

This study looks at whether daily adapted physical activity can improve sleep in children aged 5 to 16 who are being treated for blood cancer. About 30 children will take part, and their sleep quality will be tracked by parents and a sleep monitor. The goal is to see if gentle ex…

This study tests whether taking a supplement called nicotinamide riboside (a form of vitamin B3) can improve sleep quality in healthy adults aged 40 to 60. Sixteen participants will receive either the supplement or a placebo for 8 weeks, and their sleep will be measured with brai…

This study is testing whether a daily supplement called AGZ can help adults aged 25-59 who have trouble sleeping or feel stressed. About 300 people will take the supplement or a placebo for 30 days and answer questionnaires about their sleep, relaxation, and morning energy. The g…

This study tests whether SleepWhale Natural Sleep Drops can help people sleep better and feel more alert during the day. About 100 adults with sleep troubles will take the drops for 30 days and report changes in sleep quality, daytime sleepiness, fatigue, and resilience. The goal…

This study tests a comfort program for children aged 5-10 in the pediatric ICU. The program includes listening to their mother's voice, dimming the lights, and using a weighted blanket, along with regular nursing care. Researchers want to see if this helps children feel more comf…

This study tests a brief sleep program for depressed teens aged 12-18 who sleep less than 7 hours on school nights or have irregular sleep. The program uses two sessions and a smartphone app to teach healthy sleep habits. Researchers want to see if it's practical and helps improv…

This study looks at whether a supplement called MyVitalC (ESS60 in olive oil) can improve sleep and reduce headaches. About 100 adults will track their sleep and headaches for 4 weeks without the supplement, then take it daily for 6 weeks and report any changes. The goal is to se…

This study is testing whether a new dietary supplement can improve sleep quality in adults aged 35-65 who have mild sleep problems. About 140 participants will take either the supplement or a placebo for a period of time, and their sleep will be tracked using a special ring and q…

This study tests whether taking a daily 30 mg saffron extract supplement for six weeks can improve sleep quality in middle-aged adults who have mild-to-moderate sleep problems. The trial is triple-blind and placebo-controlled, meaning neither participants nor researchers know who…

This study tests whether a custom mouthpiece that gently moves the lower jaw forward during sleep can improve sleep quality, heart rate patterns, and blood oxygen levels. About 24 healthy adults aged 40-65 will wear both the active device and a placebo device to compare effects. …

This study follows 1,000 adults in Canada who are authorized to use medical cannabis for pain, sleep, anxiety, depression, or epilepsy. Researchers will track changes in symptoms and quality of life over 24 weeks using standard questionnaires. The goal is to understand how effect…

This study tests whether taking 1 ml of reishi mushroom extract every night before bed can improve sleep quality and lower stress. About 100 adults will take the extract for several weeks and report changes in sleep, fatigue, and stress levels. The goal is to see if this natural …

This study compares two digital programs—a personalized mindfulness app and a problem-solving stress management program—to see which helps first-year college students sleep longer, feel less stressed, and improve their grades. About 200 students from four universities will use on…

This study explores whether immersive virtual reality-based exercise therapy can reduce pain, improve shoulder function, sleep, and cognitive abilities in people with mild to moderate frozen shoulder (grade 1-2). Researchers will compare standard care plus VR exercise to standard…

This study is testing whether a probiotic supplement called ExoBDNF can improve memory, concentration, sleep, and mood. About 50 adults will take the supplement daily for 8 weeks. Researchers will compare their thinking and well-being before and after the trial to see if there ar…

This study tests whether a sleep bundle—including a sleep mask, earplugs, and a noise machine—can help adults sleep better after heart surgery. Twenty participants will either receive the sleep bundle or standard care. The main goal is to see if the study is practical for a large…

This study tests a sleep health program designed for U.S. Marines to see if improving sleep can also improve mental health and reduce suicidal thoughts. About 860 active-duty Marines will be randomly assigned to one of five groups that receive different combinations of sleep prog…

This study looks at how sensory sensitivities affect sleep and emotions in autistic children ages 6 to 10. Researchers will test a special bedtime routine designed to lower arousal levels in children who are overly sensitive to touch, sound, or other sensations. The goal is to se…

This study tests two types of talk therapy—cognitive behavioral therapy (CBT) and mindfulness-based therapy—to see which works better for treating insomnia and related depression in people who have had a mild to moderate traumatic brain injury (TBI) and also have post-traumatic s…

This study explores whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep, reduce brain injury symptoms, and help people with mild traumatic brain injury (mTBI) get back to their daily activities. Researchers will enroll 15 adults with mTBI and sleep problem…

This study tests two school-based programs to improve sleep in teens aged 12-18 who have sleep problems like insomnia or poor sleep quality. One program is standard sleep education, the other is a stepped-care approach. Researchers will compare which works better and for whom, es…

This study is testing whether a low dose of clonidine, a drug usually used for high blood pressure, can help veterans with PTSD sleep better and feel less stressed. About 32 veterans will take the drug for 6 weeks while researchers track changes in sleep quality, PTSD symptoms, a…

This study will test whether using a special bed cooling system (the Chilipad Dock Pro) can improve sleep quality and overall well-being. About 100 adults will use the system at home and report their sleep and health through surveys. The goal is to see if controlling bed temperat…

This study tests whether giving prebiotics (a type of fiber) daily for several weeks can improve mood, sleep, thinking, and gut health in 106 children aged 3-5 who don't get enough fiber. Parents will report on their child's behavior and emotions. The goal is to see if a simple d…

This pilot study tests a sleep improvement program designed specifically for family caregivers. Researchers want to see if combining cognitive behavioral therapy, mindfulness, and caregiving guidance can help 30 caregivers sleep more regularly, feel more rested during the day, an…

This study looks at how quickly losing water weight (dehydration) affects combat athletes' sleep, thinking skills, and leg muscle strength. Twelve athletes with experience in rapid weight loss will be monitored using sleep trackers, strength tests, and thinking quizzes. The goal …

This study looks at how healthy behaviors like diet, exercise, stress, and sleep relate to heart health in both adults and children. Researchers will collect data from questionnaires and simple health checks like blood pressure and blood sugar. The goal is to better understand th…

This study looks at how sleep, physical activity, and daily body rhythms are linked to ADHD symptoms in 200 children. Kids wear a wristband for two weeks to track movement and sleep, and complete brain scans and thinking tasks. The goal is to better understand why ADHD affects pe…

This study looks at how getting only 4 hours of sleep for three nights, or having insomnia, changes the way people process and control their emotions. Researchers will compare these groups to people with normal sleep using brain scans and emotion tasks. The goal is to better unde…

This study looks at whether a 15-minute Shoonya meditation practice can help people stay sharp and maintain healthy sleep patterns after a night of no sleep. Researchers will compare regular meditators with people who nap regularly. The goal is to understand how meditation affect…

This study aims to learn more about childhood-onset behavioral, psychiatric, and developmental disorders by examining participants of all ages and their relatives. Researchers will collect medical histories, perform thinking and behavior tests, and may use brain scans to understa…

This study aims to translate and test a sleep screening questionnaire for Turkish children with complex chronic conditions, who often have multiple health issues and sleep problems. Researchers will check if the tool is reliable and valid, and also study how common sleep issues a…

This study looks at sleep patterns in 20 teenagers aged 15-17 who have had pain for more than 3 months. Researchers want to see if a relaxing pre-sleep technique can improve sleep quality and help the brain process emotions tied to pain. Participants sleep at home with portable m…

This study looks at how sleep troubles impact memory, focus, and quality of life in women treated for breast cancer. Researchers will track sleep patterns and thinking skills in 75 patients aged 39 to 69. The goal is to find simple, non-drug ways to improve sleep and daily well-b…

This study looks at how sleep and physical activity change for blood cancer patients and their caregivers after a stem cell transplant. Researchers will ask about sleep, mood, fatigue, and quality of life through questionnaires. The goal is to understand these changes, not to tes…

This study aims to improve how sleep is measured for people who work night shifts. Current methods often fail to accurately track daytime sleep. Researchers will use multiple sensors and machine learning to create a more precise system. About 100 nightshift workers will participa…

This study looks at how using cannabis—and then stopping—changes sleep, daily rhythms, and sensitivity to light in healthy young adults aged 18-25. Researchers will compare regular cannabis users with non-users using at-home EEG headbands and light tests. The goal is to understan…

This study follows 50 people over age 50 who had arthroscopic rotator cuff repair. Researchers will measure shoulder disability, pain at rest and during movement, and sleep quality over the recovery period. The goal is to gather data to help create clearer rehab guidelines, since…

This study looks at how different light exposure and meal timing affect the body's ability to process food when sleep is limited. Researchers will monitor 120 healthy adults aged 18-35 over several months, including overnight clinic stays. The goal is to understand how these fact…

This study looks at how difficult childhood experiences and poor sleep may harm blood vessel function in young adults aged 18-29. Researchers will monitor sleep at home and test blood vessel health. Some participants will receive a 6-week sleep improvement program to see if bette…

This study looks at how the bacteria in your gut change when you get more or less sleep. About 174 adults who either sleep enough or not enough will adjust their time in bed by 1.5 hours for 14 days. Researchers will compare gut bacteria samples to see how sleep affects the micro…

This study looks at whether combining aerobic exercise (stationary biking) with planned naps can boost motor skill learning and brain function in people with relapsing-remitting multiple sclerosis. Twenty adults aged 18-70 will take part in a crossover trial, using hand skill tes…

This study looks at how getting less sleep than usual changes blood pressure. Researchers will monitor 45 healthy adults, including those with normal weight and obesity, to see if sleep restriction affects their blood pressure. The goal is to better understand the connection betw…

This study looks at how a commercially available ketone drink, Ketone-IQ, affects sleep and breathing in 20 healthy adults. Participants will take two different doses of the drink before bed at home. They will measure their ketone levels and wear a headband to track sleep pattern…

This study looks at how sleep loss and body clock disruptions impact brain circuits involved in reward and self-control in teenagers. Researchers will monitor sleep, brain activity, and hormone levels in 200 healthy teens aged 13-18. The goal is to understand how these factors ma…

This study looks at how sleep and the body's internal clock affect blood pressure in people with hypertension. Researchers will monitor 32 adults aged 25-64 to see why some people's blood pressure doesn't drop enough at night. The goal is to better understand these patterns, not …

This study looks at how smartphone and digital game addiction are linked to physical activity, sleep quality, stress, fatigue, and muscle or joint pain in university students aged 18 to 30. About 193 students will fill out questionnaires about their device use and health. The goa…

This study brings together teens (ages 12-18) living in disadvantaged urban areas in Denmark, the Netherlands, Nigeria, and South Africa with researchers and local leaders. Together, they will identify what changes in the neighborhood—like safer parks or better lighting—could hel…

This study looks at how a single night of total sleep deprivation changes certain proteins in the blood that are linked to Alzheimer's disease. Researchers want to see if these changes differ based on a person's APOE gene type, which is known to affect Alzheimer's risk. The study…

This study looks at how the COVID-19 pandemic may have changed people's physical activity, sleep, blood pressure, and mental stress. About 100 adults aged 18 to 75 will visit a lab twice, wear activity trackers for two weeks, and complete fitness tests and questionnaires. The goa…

This study looks at whether it's possible to measure sleep in regular video game players compared to non-players. Researchers will track sleep using wrist monitors, diaries, and urine tests in 40 adults aged 18 to 40. The goal is to find out what works best for a larger future st…

This study looks at whether a mobile health program called Bedtime Stories can help caregivers of children ages 5-11 improve their child's sleep. The program sends personalized sleep tips to caregivers. Researchers want to see if the program is easy to use and if it leads to bett…

This study looks at whether giving sleep tips to expecting parents can help their babies sleep longer and have fewer sleep problems. About 391 families will take part. Some parents will get regular sleep advice by email and fill out surveys, while others will not. Researchers wil…

This study explores how severe sleep deprivation in the first two days after childbirth relates to a mother's motivation to breastfeed and how well breastfeeding goes. Researchers will measure sleep problems, breastfeeding motivation, and breastfeeding success in 167 new mothers.…

This study tests whether a home-based mobile app can help parents of 3-4 year olds improve their child's daily physical activity, sleep, and screen time. About 80 children who currently meet few or no movement guidelines will wear activity trackers and have motor skills tested. P…

This study looks at whether experiencing a small time delay every day can change your internal body clock. Researchers will measure melatonin levels and reaction times in 40 healthy couples who live together. The goal is to understand how our daily routines affect sleep and circa…

This study looks at how different phases of the menstrual cycle affect walking patterns, pelvic movement, and sleep quality in healthy women aged 18 to 35 with regular cycles. Researchers will measure these factors during the early follicular, ovulation, and luteal phases using a…

This study tracks 20 adults with migraines to see how daily light exposure relates to headache frequency, pain intensity, and sleep quality. Participants wear light sensors and keep headache diaries for 8 weeks. The goal is to understand, not treat, the role of light in migraine.

This study looks at how different diets—unhealthy Western-style vs. healthy fiber-rich—affect sleep quality, heart rate, and metabolism. Researchers will monitor 24 healthy adults aged 18-32 using wearable devices and sleep tests. The goal is to understand how food choices influe…

This study looks at whether improving deep sleep can help protect the brain in older adults at risk for Alzheimer's disease. Researchers will ask 116 people aged 65-85 with mild sleep issues to spend less time in bed to naturally deepen their sleep. They will measure changes in m…