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Could CBD help people with MS sleep better and hurt less?

NCT ID NCT05269628

Recruiting now Symptom relief Sponsor: Tiffany J. Braley, MD, MS Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study investigates whether cannabidiol (CBD), a compound from cannabis, can improve sleep and reduce pain in people with multiple sclerosis (MS) who also have chronic pain. About 166 participants take CBD or a placebo for several weeks while their sleep is measured in a lab and at home. The goal is to see if CBD makes sleep more regular and less interrupted, and whether better sleep leads to less pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cannabidiol (CBD) oral solution
What this could lead to
If successful, this could point toward a new way to treat sleep problems and chronic pain in people with multiple sclerosis.
What could go wrong
This is a mid-stage trial with a moderate number of participants, so results may not apply to everyone. CBD may cause side effects like drowsiness or liver issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis Pain sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS PAIN SLEEP

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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