SLEEP

This pilot study tests whether a sleep health program designed for couples can improve sleep and blood pressure. Fifty couples will take part in an 8-week program that includes sleep education, coaching, and a Fitbit to track sleep. The goal is to see if working together as a tea…

This study tests whether a 12-week telephone health coaching program, called Support Your Heart, is practical and helpful for young adults aged 18-39 who have at least two heart disease risk factors (like poor sleep, inactivity, or high blood pressure). Twenty participants in the…

This study tests a 24-week program called Black Impact for Black men with below-ideal heart health. Participants will take part in weekly physical activity, health education, and work with a coach and trainer. The goal is to see if the program improves heart health and reduces st…

This study checks if wearable devices like movement sensors, headbands, and pulse oximeters can accurately track sleep stages in children and teens aged 3 to 18. Results will be compared with standard sleep lab tests to see if these gadgets can help diagnose sleep problems more e…

This study is testing whether wearable devices like activity trackers, EEG headbands, and smartphones can accurately measure sleep stages. Researchers will compare these devices to standard sleep lab tests (polysomnography) in 96 healthy volunteers and people with sleep disorders…

This study tests whether taking the sleep medication suvorexant (Belsomra) nightly for two years can slow the buildup of amyloid plaques in the brain, a hallmark of Alzheimer's disease. Researchers will enroll 200 healthy adults aged 65 and older with no signs of dementia. The go…

This study tests whether using the soundBrilliance app—which combines enhanced music, natural visuals, and spoken guidance—can help people aged 13 and older manage anxiety, depression, and stress. Over 12 weeks, participants use the app at least 4 days per week and report their m…

This study tests whether a gentle movement program called Body Awareness Therapy (BAT) can help young adults (ages 20-30) who feel very stressed. Over 8 weeks, one group does BAT twice a week while another group does nothing new. Researchers will measure changes in balance, sleep…

This study tests whether osteopathic manipulative treatment (OMT) — a hands-on therapy using gentle techniques on the head, neck, and ribs — can improve sleep quality in people with Parkinson's disease. Participants are split into two groups: one receives OMT, the other a light t…

This study tests a 4-week telehealth program called I-SLEPT for Veterans leaving a rehabilitation facility. The program combines sleep education and tips for staying active in meaningful activities. Researchers want to see if it is acceptable and feasible for Veterans, and whethe…

This study tests whether daridorexant, a sleep medication, can improve sleep in people with mild cognitive impairment or mild-to-moderate Alzheimer's disease who also have insomnia. Sixty-two participants will receive either the drug or a placebo for one month, and their sleep wi…

This study tests a behavioral sleep program called Care2Sleep for people with Alzheimer's disease and their caregivers. The program includes sleep hygiene, activity, and light exposure. Researchers will compare it to a sleep education group to see if it improves sleep, health, an…

This study tests whether hemp-derived CBD (with or without THC) can help older adults (60+) who use cannabis for pain, anxiety, depression, or sleep problems. Over 8 weeks, 385 participants will take either CBD+THC, CBD alone, or a placebo. The goal is to see if CBD can reduce sy…

This study tests a sleep-focused program (TranS-C) plus bright light therapy in 90 teens aged 12-18 with moderate to severe depression and sleep problems. Half get the full program with a sleep therapist and light glasses; the other half just track their sleep. The goal is to see…

This study tests two behavioral treatments—cognitive behavioral therapy (CBT) and mindfulness—to help people with traumatic brain injury (TBI) sleep better and feel less stressed. 360 veterans and service members with mild to moderate TBI, insomnia, and PTSD symptoms will receive…

This study tests two school-based sleep programs in 1,320 teens aged 12-18 with sleep problems. One program is a standard sleep health education, the other is a more intensive cognitive behavioral sleep intervention. Researchers will compare which program improves sleep quality m…

This study tests whether a daily snack rich in plant chemicals and fibre can ease perimenopause symptoms like hot flushes, mood changes, and sleep problems. Twenty women aged 40-55 who are not on hormone therapy will eat either the special snack or a placebo for several weeks, th…

This study compares two behavioral approaches to see which works better for improving mood, sleep, and reducing suicide risk in adults aged 55 and older with depression. Participants will complete interviews, questionnaires, and wear a sleep tracker for 8 weeks. The goal is to fi…

This study tests a comfort program for children aged 5-10 in the pediatric intensive care unit (PICU). The program includes listening to their mother's voice, dimming lights, and using a weighted blanket, along with regular nursing care. Researchers want to see if this helps chil…

This study looks at how sensory sensitivity affects sleep and emotions in autistic children ages 6-10. Researchers will test a simple bedtime routine called Power Down, where caregivers give their child a gentle massage to help them relax before sleep. The goal is to see if this …

This study looks at whether a custom mouthpiece that gently moves the lower jaw forward during sleep can improve sleep quality, heart rate patterns, and blood oxygen levels. About 24 healthy adults aged 40-65 will wear both the active device and a placebo device to compare effect…

This study looks at whether extending the nightly fasting period (not eating for a longer stretch each night) can improve sleep, thinking, and quality of life in breast cancer survivors. Researchers will compare this approach to health education alone. The study involves 60 femal…

This study is testing whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and daily function in 15 people with mild traumatic brain injury (mTBI) who have trouble sleeping. Participants will learn techniques like sleep scheduling and changing unhelpful tho…

This study tests whether giving 3-5 year olds a daily prebiotic fiber powder for several weeks can improve their mood, sleep, emotional control, and thinking. Parents of 106 children with low fiber intake will report on their child's behavior and emotions. The study is double-bli…

This study looks at whether taking ETAS® daily for 12 weeks can improve memory, mood, and brain activity in healthy adults aged 60 to 80 who have mild memory complaints. Participants will be randomly assigned to receive either ETAS® or a placebo, and will undergo memory tests, br…

This study tests whether a magnesium supplement called Magnesium-L-Threonate (MgT) can improve sleep quality and reduce pain in people recovering from total knee or hip replacement. Researchers will enroll 64 adults having surgery at the University of Miami Hospital. Participants…

This study tests whether a sleep health program can help U.S. Marines sleep better and feel mentally healthier. About 860 Marines will be randomly assigned to one of five groups to receive different versions of the program. Researchers will use surveys and wearable sleep trackers…

This study is testing whether taking a daily saffron extract supplement (30 mg) for six weeks can improve sleep quality in middle-aged adults who have mild-to-moderate sleep problems. Researchers will measure sleep using a wrist-worn device and track other factors like mood and s…

This study tests whether a low dose of clonidine, a drug usually used for high blood pressure, can improve sleep and reduce PTSD symptoms in veterans. About 32 veterans with PTSD will take a flexible dose of clonidine nightly for 6 weeks. Researchers will track changes in sleep q…

This pilot study tests whether a standardized sleep bundle—including a sleep mask, ear plugs, a noise machine, and stepwise medications (melatonin, then trazodone if needed)—can improve sleep for adults recovering from cardiac surgery. Twenty participants will be randomly assigne…

This study follows 1,000 adults in Canada who are authorized to use medical cannabis for pain, sleep issues, anxiety, depression, or epilepsy. Researchers will track changes in symptoms using standard questionnaires over 24 weeks. The goal is to see how well medical cannabis work…

This study looks at whether a supplement called MyVitalC (ESS60 in extra virgin olive oil) can improve sleep and reduce headaches. About 100 adults will track their sleep and headaches for 4 weeks without the supplement, then take it daily for 6 weeks and report any changes. The …

This study tests a brief behavioral sleep program for depressed teens aged 12-18 who sleep less than 7 hours or have irregular sleep. The program uses two sessions and smartphone tools to help teens set sleep goals. Researchers will compare it to a simple sleep education session …

This study is testing whether a daily supplement called AGZ can help adults aged 25-59 who have trouble sleeping feel more relaxed in the evening, sleep better, and have more energy in the morning. About 300 people will take AGZ or a placebo for 30 days and answer questionnaires …

This study tests whether a daily nutritional supplement can improve sleep quality in adults aged 35-65 who have mild sleep problems. About 140 participants will take either the supplement or a placebo for several weeks, and sleep will be tracked using a special ring and questionn…

This study tests whether a special type of artificial light that changes throughout the day can improve sleep, body clock function, and overall well-being in frail older adults. Researchers will enroll 300 people over age 65 who are staying in hospital rooms equipped with this dy…

This study tests whether taking 1 ml of reishi mushroom extract daily before bed can improve sleep quality and reduce stress. About 100 adults who can read English and live in the US will participate. The study measures sleep, fatigue, and stress using questionnaires. It is not a…

This study tests whether a special bed pad that heats or cools the mattress can help people sleep better. One hundred adults will use the Chilipad Dock Pro system at home, and researchers will track their sleep quality and well-being using surveys. The goal is to see if adjusting…

This 30-day study tests SleepWhale Natural Sleep Drops (Extra Strength) in 100 adults to see if they improve sleep quality, reduce daytime sleepiness, and boost resilience. Participants will complete surveys about their sleep, fatigue, and well-being. The study is for US resident…

This study looks at whether doing adapted physical activity every day can improve sleep quality in children aged 5 to 16 who are being treated for blood cancer. About 30 children will take part, with some exercising daily and others just once over four days. Parents will track sl…

This study tests whether immersive virtual reality (VR) exercise can reduce pain, improve shoulder function, sleep, and thinking in people with mild to moderate frozen shoulder (grade 1-2). About 36 adults aged 18-64 who are new to physiotherapy will use VR headsets to gamify the…

This study is testing whether a probiotic supplement called ExoBDNF can improve cognitive abilities like memory and concentration, as well as sleep and mood. About 50 adults aged 18 and older will take the supplement daily for 8 weeks. Researchers will measure changes using quest…

This study tests whether taking a collagen supplement for 8 days can improve quality of life, appetite, mood, and blood sugar control in overweight or obese adults aged 18-65. Participants will take the supplement or a placebo, fill out questionnaires, and wear a continuous gluco…

This study tests whether adding bright light therapy, a stimulant (methylphenidate), or melatonin to cognitive behavior therapy can improve sleep and related symptoms like fatigue, anxiety, and depression in 188 adults with advanced cancer. Participants will receive one of these …

This study tests whether morning bright light therapy can improve sleep and brain function in 105 adults recovering from opioid use disorder. Participants on stable medication will receive either bright or dim light for 30 minutes daily over two weeks. Researchers will measure sl…

This pilot study tests whether taking a form of Vitamin B3 (nicotinamide riboside) can improve sleep quality in healthy adults aged 40-60. Sixteen participants will receive either the supplement or a placebo for 8 weeks, and their sleep will be measured with brainwave monitoring.…

This study investigates whether the match between a person's chronotype (morning or evening preference) and the time of day influences how they perceive time. Healthy adults who are clear morning or evening types complete perception and cognition tasks both early in the morning a…

This early-stage study at Stanford tests whether giving magnetic brain stimulation during sleep is safe and practical for people with major depression. Fifteen adults who have not gotten better with at least one antidepressant will receive both real and fake stimulation in separa…

This study aims to learn more about childhood-onset behavioral, psychiatric, and developmental disorders by observing people of all ages who have these conditions, along with their family members. Researchers will collect medical histories, perform psychiatric assessments, and ma…

This study looks at how things like air quality, noise, and light in hospital wards affect patients' sleep. Researchers will measure these factors and track the sleep of 120 adult patients who stay at least two nights. The goal is to understand the hospital environment better and…

This study aims to understand how the light from tablet screens and the type of content children watch before bed affect their sleep, thinking skills, and emotions. Researchers will have 220 children aged 8 to 11 spend one hour before bed either using a bright tablet, a dim table…

This study looks at how sleep helps clean the brain. Researchers will use special MRI scans to see the brain's waste-clearing system in 16 healthy young adults. They will also test a headband that tracks brain waves and uses mild electrical pulses to improve sleep and brain funct…

This study tests whether morning bright light therapy can improve sleep in 300 veterans with traumatic brain injury. Researchers will measure changes in inflammation, energy production in cells, and brain cleaning systems. The goal is to understand how better sleep might support …

This study aims to understand why many patients have poor sleep after scheduled surgery. Researchers will give questionnaires to 1,000 adults undergoing general anesthesia to measure sleep quality and daytime drowsiness. The goal is to identify factors that disrupt sleep, such as…

This study looks at whether giving tube feedings during the day instead of at night can improve sleep and body rhythms in patients recovering from heart surgery in the ICU. Researchers will monitor sleep patterns and body temperature in 30 adults. The goal is to learn if simple c…

This study looks at how pregnant women sleep, focusing on the positions they spend the most time in and how often they snore. About 500 women who are at least 28 weeks pregnant will use a sleep monitor at home. The goal is to learn more about sleep patterns during pregnancy and s…

This study looks at how daily light patterns relate to migraine headaches and sleep quality in adults. Over 8 weeks, 20 participants will track their migraines, light exposure, and sleep using diaries and devices. The goal is to understand these connections, not to test a new tre…

This study looks at how sleep changes affect the bacteria in your gut. Researchers will ask people who sleep too little to sleep more, and people who sleep enough to sleep less, for 14 days. They want to see if these sleep changes alter the types and amounts of gut bacteria. The …

This study is translating a sleep screening questionnaire into Turkish and testing how well it works for children with complex chronic conditions. Researchers will enroll 330 children and teens, tracking their sleep at home and during stays in the pediatric intensive care unit. T…

This study looks at how getting only 4 hours of sleep for three nights, or having insomnia, changes the way people process and control their emotions. Researchers will use brain scans and behavioral tests to compare these groups with people who sleep normally. The goal is to bett…

This study tests a new computer program that reads brain activity to tell if someone is conscious or not. Thirty healthy adults will have their brains scanned while awake and asleep. The goal is to see if a simpler, portable version of the test can accurately detect consciousness…

This study looks at how sleep and body clocks affect the brains of teenagers and their risk for using substances like alcohol or drugs. Researchers will monitor the sleep patterns and brain activity of 200 healthy teens aged 13-18. The goal is to understand how changes in sleep a…

This study looks at how cannabis use and stopping it affect sleep, daily body rhythms, and sensitivity to light in healthy young adults aged 18-25. Researchers will compare regular cannabis users with non-users using sleep monitors, light tests, and pupil measurements. The goal i…

This study is testing whether giving expecting parents sleep information and advice can help their babies sleep longer and have fewer sleep problems. About 391 families will be followed for 24 months, with some receiving regular sleep tips and others none. The goal is to see if s…

This study explores how severe sleep deprivation in the first 48 hours after childbirth impacts a mother's motivation to breastfeed and her breastfeeding success. Researchers will track 167 new mothers, including those who had C-sections, using surveys and feeding assessments. Th…

This study looks at what happens to blood pressure when healthy adults sleep only 4 hours a night. Researchers will compare normal-weight and obese participants to see if lack of sleep affects their blood pressure differently. The goal is to better understand the link between sle…

This study aims to improve how sleep is measured for nightshift workers, whose inverted schedules make standard sleep trackers inaccurate. Researchers will use an Apple Watch along with machine learning to better detect daytime sleep. About 100 nightshift workers will participate…

This study tests a new program called Bedtime Stories that sends tailored sleep health messages to caregivers of school-aged children (ages 5-11) from low-income and historically marginalized communities. The goal is to see if the program is easy to use and helps improve children…

This study looks at how quickly losing weight through dehydration (using a sauna) affects combat athletes' sleep quality, thinking skills, and leg strength. Twelve athletes with prior weight-cutting experience will be monitored before and after losing 3% of their body weight. The…

This study looks at how sleep and physical activity change for blood cancer patients and their caregivers after a stem cell transplant. Researchers will use a Fitbit to monitor activity, sleep, and heart rate, and ask participants to complete questionnaires about their quality of…

This study looks at how sleep, physical activity, and daily rhythms relate to ADHD symptoms and brain function in 200 children. Kids wear a wristband for two weeks and complete cognitive tests and MRI scans. The goal is to better understand why ADHD affects people differently and…

This study looks at how sleep and the body's internal clock influence blood pressure in people with hypertension. Researchers will monitor 32 adults aged 25-64 to understand why some have a 'non-dipping' pattern where blood pressure stays high at night. The goal is to uncover mec…

This study aims to see if it's practical to measure sleep in adults who play video games regularly but don't have gaming disorder. Forty participants (gamers and non-gamers) will keep sleep and gaming diaries, wear a wrist monitor, and provide urine samples for melatonin testing.…

This study from Uppsala University looks at how a low-fat, fiber-rich diet versus a high-fat, Western-style diet affects sleep quality, heart rate, and metabolism. Twenty-four healthy young adults will follow each diet for about a week, then spend two days in the lab for detailed…

This study looks at how different patterns of light exposure and food intake affect the body's metabolism when sleep is reduced. Researchers will monitor 120 healthy adults aged 18-35 over 4-6 months, including three overnight clinic stays. The goal is to understand how these fac…

This study looks at how a commercially available ketone drink (Ketone-IQ) affects sleep and breathing in 20 healthy adults aged 18-50. Participants take two different doses at home on separate nights and measure their ketone levels and sleep quality using a headband device. The g…

This study looks at whether experiencing a one-hour time delay every day can shift your body's internal clock. Researchers will measure melatonin levels and reaction times in 40 healthy couples who live together. The goal is to understand how our daily routines affect sleep and c…

This study tests whether a short burst of aerobic exercise on a stationary bike and a 30-minute nap can improve how people with multiple sclerosis learn and remember a hand motor skill. Twenty adults with relapsing-remitting MS will take part. Researchers will measure brain and m…

This study looks at how a full day without sleep changes certain proteins in the blood that are linked to Alzheimer's disease. Researchers want to see if people with different versions of the APOE gene react differently to sleep loss. The study involves 60 healthy adults aged 18 …

This study tests whether spending less time in bed for four weeks can deepen sleep and boost memory in adults aged 65-85 who have poor sleep and are at risk for Alzheimer's. Researchers will measure brain activity, memory, and blood markers. The goal is to see if a simple behavio…

This study tests a 12-week mobile app program for parents of 3-4 year olds who currently meet few movement guidelines. Children wear activity trackers, and parents get weekly tips and goals through the app. The goal is to see if the app helps kids get more physical activity, bett…

This study looks at how difficult childhood experiences and poor sleep might harm blood vessel function in young adults aged 18-29. Researchers will monitor sleep at home and test blood vessel health. Some participants will receive a 6-week sleep therapy program (CBT-i) to see if…

This study is looking at how lifestyle choices like diet, exercise, stress, and sleep relate to heart health measures such as blood pressure and cholesterol. Researchers will ask 100 adults and young people to fill out a questionnaire about their habits. The goal is to better und…

This study from Indiana University looks at how the COVID-19 pandemic may have changed people's physical activity, sleep, diet, blood pressure, and mental stress. Researchers will track 100 adults aged 18-75 using wearable devices, fitness tests, blood samples, and blood pressure…

This study looks at how sleep disturbances impact thinking skills and quality of life in 75 women treated for breast cancer. Participants will undergo brain scans, sleep tracking, and cognitive tests over six months. The goal is to understand the links between sleep, brain functi…

This study, called YoPA, is testing whether getting teenagers directly involved in designing changes to their neighborhoods can help them be more active, sleep better, and spend less time on screens. Researchers in Denmark, the Netherlands, Nigeria, and South Africa will work wit…

This study looks at how chronic pain affects sleep in teenagers aged 15-17. Researchers will test whether listening to a relaxing story before falling asleep can improve sleep quality and help process emotions related to pain. Twenty teens with persistent pain will have their sle…

This study is testing a new physical therapy protocol for people over 50 who have had arthroscopic rotator cuff surgery. Researchers will track shoulder function, pain levels, and sleep quality over the recovery period. The goal is to gather better evidence on what helps patients…