CBD put to the test as a smoking reduction aid

NCT ID NCT06218056

Recruiting now Disease control Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether cannabidiol (CBD), a compound from hemp, can help people who want to quit smoking reduce their cigarette use. 120 adults with tobacco use disorder will receive either CBD or a placebo twice daily for 56 days. Researchers will measure nicotine levels and check if participants can stay smoke-free.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabidiol (CBD)
What this could lead to: If successful, this could point toward a new option to help people cut down or quit smoking, especially those who struggle with existing treatments.
What could go wrong: This is a mid-stage trial with 120 people, so results may not apply broadly. CBD may not reduce smoking more than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Cessation Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TOBACCO DEPENDENCE TOBACCO SMOKING TOBACCO USE DISORDER

Contacts and locations

Locations

CRI-Help, Inc.
RECRUITING

North Hollywood, California, 91601, United States

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