Could a synthetic cannabis drug soothe Alzheimer's agitation?
NCT ID NCT04516057
First seen Jan 28, 2026 · Last updated May 15, 2026 · Updated 16 times
Summary
This study tests whether nabilone, a synthetic cannabinoid already approved for nausea, can safely reduce agitation in people with Alzheimer's disease. Agitation is common and distressing, and current treatments have limited effectiveness and side effects. About 112 participants will receive either nabilone or a placebo for 8 weeks, with follow-up for another 8 weeks. Researchers will also check effects on mood, pain, nutrition, and caregiver stress.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre for Addiction and Mental Health
RECRUITINGToronto, Ontario, Canada
Contact Email: •••••@•••••
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London Health Sciences Centre
RECRUITINGLondon, Ontario, N6A 5W9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ontario Shores Centre for Mental Health Sciences
RECRUITINGWhitby, Ontario, L1N 5S9, Canada
Contact Email: •••••@•••••
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St. Michael's Hospital
RECRUITINGToronto, Ontario, Canada
Contact Email: •••••@•••••
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Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Calgary
RECRUITINGCalgary, Alberta, T2N 4N1, Canada
Contact Email: •••••@•••••
Conditions
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