Scientists scan brains to uncover cannabinoid receptor secrets in mental illness and addiction
NCT ID NCT01730781
First seen Apr 29, 2026 · Last updated Jun 21, 2026 · Updated 13 times
Summary
This study uses a special PET scan tracer called [11-C]OMAR to measure cannabinoid receptors in the brain. Researchers will compare healthy volunteers to people with schizophrenia, cannabis dependence, PTSD, opioid use disorder, and other conditions. The goal is to understand how these receptors differ across disorders, which may inform future research. Participants receive one or more PET scans, and cannabis users will be scanned at different stages of abstinence.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Connecticut Mental Health Center, Clinical Neuroscience Research Unit
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
[11-C]OMAR (a radioactive tracer for PET scans)
What this could lead to
If successful, this could help researchers understand how brain cannabinoid receptors differ in various mental health and addiction conditions, potentially guiding future treatments.
What could go wrong
This is an observational imaging study, not a treatment trial. It is early-stage research and may not directly lead to new therapies. Results may not apply to all populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.