Could a new pill for schizophrenia pass its first human test?

NCT ID NCT06105151

First seen Aug 14, 2026 ยท Last updated Aug 14, 2026

Summary

This early-stage trial evaluates an experimental oral drug called VV119, which is being developed for schizophrenia. The study enrolls healthy volunteers to receive a single dose of VV119 or a placebo, with some participants taking it with food to see if meals affect how the drug is absorbed. Researchers will monitor safety, side effects, and how the drug moves through the body. This is a first step to determine if VV119 is safe enough to study further in people with schizophrenia.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
VV119, an experimental oral drug being tested for schizophrenia
What this could lead to
If successful, this early trial could pave the way for a new oral medication option for schizophrenia, potentially offering better tolerability or convenience.
What could go wrong
This is a very early phase 1 study in healthy people, not patients. It primarily checks safety and how the drug behaves, so it may not lead to an effective treatment, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Anding Hospital of Capital Medical University

    Beijing, Beijing Municipality, 100088, China

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Other studies related to the condition(s) this trial covers.