Ancient herbal blend put to the test against Drug-Induced constipation

NCT ID NCT07767526

First seen Aug 17, 2026 ยท Last updated Aug 17, 2026

Summary

This trial investigates whether a traditional Chinese medicine formula, Xingqi Daozhi Decoction, can relieve constipation that often occurs as a side effect of antipsychotic medications in people with schizophrenia. The study will enroll 46 adults with schizophrenia who have developed constipation, and randomly assign them to receive either the herbal granules or a placebo twice daily for 8 weeks. Neither participants nor researchers will know who gets which treatment. The main goal is to see if the herbal formula improves the frequency and completeness of spontaneous bowel movements, while also monitoring safety and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Xingqi Daozhi Decoction, a traditional Chinese herbal formula
What this could lead to
If effective, this herbal remedy could offer a new, well-tolerated option to relieve constipation in people taking antipsychotic medications, potentially improving comfort and treatment adherence.
What could go wrong
This is an early-stage exploratory trial with a small number of participants, so results may not be conclusive or widely applicable. Herbal remedies can also have side effects or interact with other medications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Mental Health Center

    Shanghai, China

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