Brain scans reveal hidden synaptic changes in mental illness
NCT ID NCT03995121
First seen Jan 28, 2026 · Last updated Jun 11, 2026 · Updated 21 times
Summary
This study uses a special brain scan (PET) with a new tracer called [11C]APP311 to measure synaptic density in people with psychotic disorders or cannabis use disorder, compared to healthy volunteers. The goal is to understand how brain connections differ in these conditions. Researchers will also test if these differences relate to thinking skills and brain wave patterns.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Conneticut Mental Health Center
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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