Brain scan study seeks to uncover synaptic secrets in mental illness

NCT ID NCT03995121

First seen Jan 28, 2026 · Last updated May 01, 2026 · Updated 14 times

Summary

This study uses a special brain scan (PET) with a new tracer called [11C]APP311 to measure synaptic density—the connections between brain cells—in people with psychotic disorders or cannabis use disorder, compared to healthy volunteers. Researchers aim to understand how these connections differ in psychiatric conditions and how they relate to thinking and brain activity. The study enrolls 250 adults aged 18 to 65.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Conneticut Mental Health Center

    RECRUITING

    New Haven, Connecticut, 06519, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.