Stress pills may reveal why you crave cannabis

NCT ID NCT06430580

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study gives people with Cannabis Use Disorder drugs that mimic stress to see how it affects their desire for cannabis. Researchers measure brain activity and decision-making during four lab visits. The goal is to understand the link between stress and cannabis use motivation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hydrocortisone and Yohimbine Hydrochloride

What this could lead to

If successful, this could help explain how stress triggers cannabis cravings, pointing toward better treatments for Cannabis Use Disorder.

What could go wrong

This is a very early, small study (36 people) testing temporary stress-like effects, not a treatment. Results may not lead to real-world therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cannabis dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The BRAINS Lab at Florida State University

    RECRUITING

    Tallahassee, Florida, 32306-4301, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••