Brain scans reveal hidden links between depression, cannabis, and HIV in young adults

NCT ID NCT05453513

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study investigates how depression and cannabis use together affect brain circuits involved in reward and pain in young people living with HIV. Researchers will use MRI scans and questionnaires to measure brain activity, mood, and substance use. The goal is to understand why these conditions often occur together and how they may worsen health outcomes over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could reveal how depression and cannabis use interact in young people with HIV, pointing toward better mental health and addiction treatments.

What could go wrong

This is an observational brain-imaging study, not a treatment trial. It may not lead to direct clinical changes, and results may not apply to all people with HIV.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Depression depressive disorder HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact