Can CBD tame cannabis addiction? new study investigates

NCT ID NCT07434895

Recruiting now Knowledge-focused Sponsor: Hannah Harris Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 13, 2026 · Updated 7 times

Summary

This early-phase study is looking at how cannabidiol (CBD) affects the appeal and pain-relieving effects of cannabis. Researchers will give 23 healthy adults different doses of CBD for 14 days and then measure how much they like active cannabis and how it changes their pain sensitivity. The goal is to see if CBD can reduce cannabis abuse liability without blocking its pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cannabidiol (CBD) and active cannabis
What this could lead to: If successful, this study could help understand whether CBD can reduce the addictive potential of cannabis while preserving its pain-relieving effects.
What could go wrong: This is a very small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world cannabis users or those with pain conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABUSE LIABILITY CANNABIS EXPERIMENTAL PAIN IN HEALTHY HUMAN PARTICIPANTS

Contacts and locations

Locations

University of Kentucky
RECRUITING

Lexington, Kentucky, 40508, United States

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