Natural hormone may counteract cannabis high
NCT ID NCT07216690
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study tests whether a natural hormone called pregnenolone can reverse the effects of cannabis intoxication. Researchers at Johns Hopkins will give 20 healthy adults who have used cannabis before either pregnenolone or a placebo, then measure changes in drug effects, thinking skills, and vital signs. The goal is to see if pregnenolone could be used in emergencies to treat cannabis overdose or intoxication.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Johns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit
RECRUITINGBaltimore, Maryland, 21224, United States
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