Hormone pill may counteract cannabis high, early study hopes

NCT ID NCT07216690

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 23 times

Summary

This study tests whether a natural hormone called pregnenolone can reverse the effects of cannabis intoxication. Twenty healthy adults who have used cannabis before will receive either pregnenolone or a placebo in random order. Researchers will measure changes in drug effects, thinking skills, and vital signs to see if pregnenolone can reduce intoxication symptoms.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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