Brain zaps may reveal why heavy cannabis users ignore their own problems

NCT ID NCT06907979

Recruiting now Knowledge-focused Sponsor: Auburn University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive brain stimulation technique called TMS can change how people with severe cannabis use disorder recognize their cannabis-related problems. Twenty-four participants will receive real and sham TMS while researchers measure brain activity and emotional responses. The goal is to understand the brain mechanism behind problem recognition, not to treat the disorder directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If it works, this could point toward a brain-based treatment to help people with cannabis use disorder better recognize and address their cannabis-related problems.
What could go wrong: This is a very small, early-stage study (24 people) testing a mechanism, not a treatment. It may not lead to any practical therapy, and TMS can cause mild discomfort or headache.

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Conditions

The condition(s) this trial relates to.

cannabis dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS USE DISORDER, SEVERE

Contacts and locations

Locations

Auburn University Neuroimaging Center
RECRUITING

Auburn, Alabama, 36849, United States

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