Hormones may hold key to cannabis addiction recovery
NCT ID NCT04964739
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how sex hormones and gender influence recovery from cannabis use disorder. 224 adults who wanted to cut down on cannabis received 8 weeks of counseling, including one-on-one goal setting and computerized therapy. They also provided daily saliva samples to track hormone levels. The goal was to see if hormones like progesterone affect the chance of achieving remission.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Cognitive Behavioral Therapy (CBT4CBT)
- What this could lead to
- If successful, this could help personalize cannabis use disorder treatments based on sex hormones.
- What could go wrong
- This is an observational study, not a treatment trial. Results may not lead to new therapies.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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