Cannabis compounds tested to fight HIV brain inflammation

NCT ID NCT05514899

First seen May 06, 2026

Summary

This study looks at how CBD and THC, two compounds found in cannabis, affect inflammation and brain health in people with HIV. About 90 participants will take both substances in a random order over six weeks. Researchers will measure blood markers and brain function to better understand how cannabis interacts with HIV-related inflammation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • HIV Neurobehavioral Research Program (HNRP)

    RECRUITING

    San Diego, California, 92103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cannabidiol (CBD) and tetrahydrocannabinol (THC)

What this could lead to

If successful, this could point toward new ways to reduce inflammation and brain problems in people with HIV.

What could go wrong

This is a small, early-stage study focused on understanding, not treatment. Results may not lead to any new therapies, and cannabis can have side effects like dizziness or mood changes.

Conditions

The condition(s) this trial relates to.

cannabis dependence HIV infectious disease Neuroinflammatory Diseases neuronitis thrombocytopenia 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.