CBD may help young adults quit cannabis by easing stress and withdrawal

NCT ID NCT05885542

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how cannabis use and stress affect each other in young adults aged 18-25 with cannabis use disorder. Researchers will test whether a single dose of cannabidiol (CBD) can reduce withdrawal symptoms and stress, and delay the urge to use cannabis again. The goal is to understand sex differences and guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cannabidiol (CBD) oral solution
What this could lead to
If successful, this could point toward a tailored treatment for cannabis use disorder that helps young adults manage stress and reduce withdrawal symptoms.
What could go wrong
This is an early-phase study with a small sample, so results may not apply broadly. CBD may not significantly reduce stress or withdrawal, and participants can resume cannabis use during the trial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

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