Weight-Loss drug semaglutide tested as cannabis craving cure

NCT ID NCT07523633

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether semaglutide (Wegovy), a drug used for weight loss, can help adults with cannabis use disorder use less cannabis. 100 participants will receive either semaglutide or a placebo injection weekly for 20 weeks. The main goal is to see if the drug reduces total cannabis use compared to placebo, with brain scans in some participants to explore how it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide (Wegovy)

What this could lead to

If it works, this could offer a new medication to help people cut down or stop cannabis use, addressing a condition with few approved treatments.

What could go wrong

This is an early Phase 2 trial with only 100 people, so results may not apply broadly. Semaglutide can cause nausea, vomiting, and other side effects, and the placebo group may also improve.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cannabis dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Psychiatric Center Copenhagen, Frederiksberg Hospital

    RECRUITING

    Frederiksberg, 2100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••