THC study: does age change how cannabis affects you?

NCT ID NCT05865470

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how age and sex influence the effects of THC, the main psychoactive ingredient in cannabis. Researchers will give smoked and oral THC to 103 adults aged 18-65 who use cannabis regularly. They will measure pain relief, intoxication, impairment, and how the body processes THC. The goal is to understand why people react differently to cannabis based on age and sex.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Delta-9-THC (the active ingredient in cannabis)

What this could lead to

If successful, this study could help doctors understand how THC affects people differently based on age and sex, potentially leading to safer cannabis use guidelines.

What could go wrong

This is an early-phase study with only 103 participants, so results may not apply to everyone. It focuses on short-term effects, not long-term safety or benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Coitus Pain poisoning substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UCLA Center for Cannabis and Cannabinoids

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••