STRESS

This study tests two approaches—lifestyle medicine consultations and cognitive behavioral therapy (CBT)—to reduce cardiovascular risk in autistic individuals aged 9 to 26 who have a high body mass index. Participants are randomly assigned to receive lifestyle coaching, CBT sessio…

This study tests whether a 12-week program of supervised exercise, Mediterranean diet education, and stress management workshops can improve health in 120 overweight or obese adults. Participants will wear a smart bracelet to track activity and sleep. Researchers will measure cha…

This observational study will enroll 440 Danish-speaking adults over 50 to see if an artificial intelligence model can detect dementia and mild cognitive impairment from speech recordings. Participants will complete standard cognitive tests and describe a picture while being reco…

This study tests a personalized support program called PTBCARE+ for pregnant individuals at high risk of delivering early. The program includes a stress reduction toolkit, a website/app, care coordination, and optional massage. Researchers will compare stress levels and birth out…

This study tests whether a set of four gentle osteopathic manual techniques can reduce stress and anxiety in young adults aged 18 to 35. Thirty participants will either receive the real techniques or a placebo simulation, and researchers will measure changes in heart rate variabi…

This study looks at whether the herb ashwagandha can lower stress in healthy women aged 18-45 who feel moderately stressed. Researchers will measure stress hormones and heart rate over 8 weeks. The goal is to see if ashwagandha improves wellbeing without major side effects.

This study tests whether a non-electric, hand-held temple massager—used daily for 4 weeks with a special lotion and optional lavender aromatherapy—can lower stress, improve emotional wellbeing, sleep quality, and overall quality of life in women aged 35 to 65. Participants use th…

This pilot study will test whether a weekly 60-minute sound bowl meditation, offered for six weeks, can lower stress and anxiety in unpaid caregivers. Forty adult caregivers who have been helping a chronically ill or disabled family member or friend for at least six months will p…

This study tests whether doing a short 5-minute breathing or mindfulness exercise every day for a month can help Spanish-speaking university students feel less anxious and stressed. 240 participants will be split into four groups, each using a different technique like box breathi…

This study tests whether a daily collagen supplement called AP-Brain can improve attention, focus, and memory in adults aged 35-70 who are stressed but otherwise healthy. Seventy-two participants will take either a higher or lower dose for 56 days and complete memory tasks and st…

This study tests an online platform called PURSUIT that teaches coping skills to Michigan youth aged 8-18 and their caregivers. The program provides cognitive-behavioral techniques for managing pain, stress, and mood, with extra substance use prevention content for teens 12 and o…

This study tests whether doing balance exercises (like walking backward or standing on one leg) while also performing mental tasks (like counting or memory games) can lower stress and improve balance in healthy university students aged 18 to 25. Seventy-two participants will be s…

This study will test whether listening to an audiobook before total knee replacement surgery can lower patients' anxiety, blood pressure, and pulse rate. About 93 adults scheduled for elective knee replacement will be asked to use an audiobook app before their operation. Research…

This study tests a single 90-minute therapy session for teens aged 13-18 who have experienced trauma and are waiting for longer treatment. The session teaches coping skills and understanding of trauma cues. About 40 teens in New Zealand will take part to see if this approach is p…

This study tests whether short, playful activities—like guided drawing, gentle body movement, and acceptance therapy—can reduce stress and anxiety in university students during exams. Sixty students will participate in a single 20-minute session, and a subgroup will have their br…

This Stanford study tests whether a short virtual reality mindfulness session can improve mental well-being and reduce anxiety in hospitalized adults. 42 participants will try the VR app and also receive standard care, acting as their own comparison. The goal is to see if immersi…

This study tests an 8-week mindfulness program designed to help nursing students reduce stress, anxiety, and depression while improving their emotional control. About 93 students will learn meditation, breathing exercises, and mindful movement. The goal is to see if these techniq…

This study will test whether an open-label placebo nasal spray (a spray with no active ingredients, clearly labeled as a placebo) can reduce stress in 260 adults about to do a canyon swing. Participants will either use the spray or receive no treatment. Researchers will measure s…

This study tests whether listening to a 30-minute audio track with special binaural beats (adjusted by brain activity) can reduce stress and improve thinking in 32 college music students preparing for a concert. Participants will have brain scans before and after listening to eit…

This study tests a mindfulness program designed to help sexual assault survivors reduce alcohol misuse and tobacco use. Researchers will enroll 120 college students aged 18-24 who have experienced sexual violence and drank alcohol recently. Participants will take online surveys a…

This study tests a program called CommunityRx-Dementia, where trained peer mentors help caregivers of people with dementia. Over 12 months, caregivers get a personalized list of community resources, coaching, and supportive text messages. The goal is to reduce loneliness and help…

This study tests whether using a stress ball during a prostate biopsy can lower anxiety, pain, and stress. About 72 men will be randomly assigned to either use a stress ball or receive standard care. The goal is to see if this simple, low-cost tool improves the procedure experien…

This study tests a program called CALM that helps Black adults with asthma cope with stress. Researchers want to see if the program is practical and well-liked by participants. About 50 adults who have persistent, uncontrolled asthma and moderate-to-high stress will take part.

This study tests whether taking a daily probiotic supplement for 8 weeks can reduce stress and anxiety in healthy university students during exam time. Two hundred students will receive either the probiotic or a placebo. Researchers will measure changes in stress, anxiety, sleep …

This pilot study tests an online program for parents of children with hearing loss who have recently had cochlear implant surgery. The program combines education about implant care and communication strategies with Acceptance and Commitment Therapy (ACT) to help parents manage st…

This study tests whether a 10-minute virtual reality (VR) relaxation session can lower stress in healthcare workers before they enter the operating room. About 80 volunteers will either use a VR headset or sit in a quiet room, and their heart rate and stress levels will be measur…

This study tests whether a voice-based program called Talk Parenting, delivered through an Amazon Echo Dot, can help parents of children ages 3-5 improve challenging bedtime and morning routines. About 184 families will either use the program right away or wait 6 weeks. Researche…

This study looks at whether racism-related stress affects how well a digital cognitive behavioral therapy program (Sleepio) works for insomnia in Black adults. One hundred participants will use the app for 6-10 weeks while researchers track their sleep and stress levels. The goal…

This study tests whether two dietary supplements can help adults who are poor sleepers improve their sleep quality, thinking skills, and stress levels. Over 28 days, 68 participants will take either an active supplement or a placebo. Researchers will measure sleep efficiency, gut…

This study looks at whether watching a nature-based virtual reality video while listening to special sound patterns (binaural beats) can help people relax. 18 healthy adults will try both the VR experience and a control session. The researchers will measure heart rate changes and…

This study tests whether a gentle hand-application method called Jin Shin Jyutsu can help perimenopausal women feel better emotionally and physically. Sixty women aged 40-54 will practice the technique daily for two weeks. Researchers will measure changes in quality of life, stre…

This study tests whether a small, home-use ear stimulation device can improve sleep and reduce stress in health sciences students who have trouble sleeping. Sixty students will either receive active stimulation or a placebo for three weeks. The goal is to see if this easy, non-in…

This study tests whether a special type of acupressure—timed to the body's natural daily rhythms—can improve sleep in nursing home residents aged 60 and older. Eighty participants will receive either real or fake acupressure twice a day for four weeks. Researchers will measure sl…

This study tests whether a three-week online mindfulness program can lower stress, boost resilience, and improve academic confidence in nursing students in Somalia. Fifty students will be randomly assigned to either the mindfulness group or a no-intervention control group. The pr…

This study looks at whether using a weighted blanket can reduce nighttime leg cramps, improve sleep quality, and lower anxiety and stress in pregnant women. Fifty women in their third trimester will use the blanket for 14 days and compare results to a 14-day period without it. Th…

This study will test whether short office massages—on the head, neck, or hands—can lower chronic stress in women with sedentary jobs. 140 participants will receive 15-minute massages twice a week for four weeks, while a control group rests quietly. Researchers will measure stress…

This study tests whether a positioning device called Swaddy® can reduce stress in premature newborns resting in incubators. About 56 babies weighing 1500 grams or less will be observed for 3 hours on two separate days—one with the device and one without. Researchers will measure …

This study tests whether using a virtual reality headset during a breast biopsy can lower depression, anxiety, and stress. 80 women will either wear a VR headset showing calming nature scenes or receive standard care. Researchers will measure their mood before and after the proce…

This pilot study tests whether a daily lemon balm supplement can improve mood and reduce stress in healthy adults. Forty volunteers will take either the supplement or a placebo for 3 weeks. Researchers will measure changes in stress perception and cortisol levels.

This study looks at whether teaching mindfulness skills to pregnant women admitted to the hospital for risk of preterm delivery can reduce their depression, anxiety, and stress. Researchers will enroll 60 mothers and provide four weeks of mindfulness training. Participants will f…

This study tests a gentle exercise method called global postural reeducation in 30 housewives aged 25-40 who have had low back pain for over 3 months. The goal is to see if it can reduce pain, lower stress, and improve sleep quality. Unlike painkillers, this approach focuses on r…

This study looks at whether a short, 10-minute virtual reality session with biofeedback can help healthcare workers on surgical wards feel less stressed and more satisfied at work. About 75 nurses, residents, and surgeons will try it once during their shift. The goal is to see if…

This study looks at how a 12-week aerobic exercise program affects brain activity and stress hormones in veterans with overweight or obesity. Researchers will use brain scans and stress tests to see if exercise changes how participants react to pictures of high-calorie foods and …

This study looks at whether mindfulness-based stress reduction can help Black teenage girls who have been involved with the justice system and their parents or caregivers. About 90 participants will report on stress, PTSD symptoms, and other outcomes before and after the program.…

This study tests whether shining red/near-infrared light on the neck and inside the nose (called photobiomodulation) can improve how the body handles stress. Forty healthy adults will undergo a stressful test while wearing either a real or sham light device. Researchers will meas…

This study in Côte d'Ivoire tests whether giving mothers a cash reward for breastfeeding until their child is 24 months old increases breastfeeding rates and improves child and maternal health. About 1,040 mothers will either receive the cash incentive or just educational materia…

This study will test whether reducing recreational screen use to 1 hour per day for 4 weeks can improve mental well-being, sleep, and social interaction in 240 young people aged 13 to 24. Participants will either cut their screen time or continue as usual, and researchers will tr…

This study looks at whether a hands-on exam called OSCE (Objective Structured Clinical Examination) changes stress levels and IV insertion skills in nursing students. Fifty-two students will be split into two groups: one takes the OSCE, the other does not. Stress is measured with…

This study explores whether stress in children and their parents is related to bruxism (teeth grinding) in kids aged 8-11. Researchers will compare 100 children with and without bruxism, using questionnaires to measure stress levels. The goal is to better understand the role of s…

This study will test whether 15 minutes of moderate cycling or a specific breathing technique called cyclic sighing can reduce stress and improve thinking in 30 healthy young adults. Participants will try both activities a week apart, and researchers will measure brain waves, hea…

This pilot study tests a 3-5 minute recorded message called PEACE, designed to improve mental wellbeing and public attitudes toward reintegrating former Boko Haram members in Nigeria. Researchers will enroll 74 adults to see if the intervention is acceptable and feasible. The goa…