Exercise may rewire Veterans' brains to curb stress eating

NCT ID NCT06627569

Not yet recruiting Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times

Summary

This study looks at how a 12-week aerobic exercise program affects brain activity and stress hormones in veterans with overweight or obesity. Researchers will use brain scans and stress tests to see if exercise changes how participants react to pictures of high-calorie foods and mental math challenges. The goal is to understand the link between exercise, stress, and eating behaviors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: aerobic exercise
What this could lead to: If successful, this could reveal how exercise helps reduce stress-related overeating, pointing toward better weight management strategies for veterans.
What could go wrong: This is an early-stage observational study with no treatment outcome—it measures brain activity and hormone changes, not weight loss. Results may not lead to a direct intervention.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERWEIGHT , OBESITY STRESS

Contacts and locations

Locations

Rocky Mountain Regional VA Medical Center, Aurora, CO

Aurora, Colorado, 80045-7211, United States

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