STRESS

This study tests whether installing energy recovery ventilators or portable air cleaners in low-income homes can reduce indoor pollutants and mold, and improve asthma control. Researchers will monitor 80 households over one year, measuring lung function, asthma symptoms, and qual…

This study tests whether an online sleep improvement program for pregnant women can reduce stress and prevent postpartum depression and anxiety. Researchers will enroll 114 women early in pregnancy and track their sleep, stress hormones, and mood for months after birth. The progr…

This study tests whether squeezing a stress ball during oral care procedures helps lower pain, anxiety, and stress in conscious intensive care patients. Participants will be randomly assigned to use a stress ball or receive standard care. The goal is to see if this simple, low-co…

This study tests whether a gentle movement program called Body Awareness Therapy (BAT) can help young adults (ages 20-30) who feel very stressed. Over 8 weeks, one group does BAT twice a week while another group does nothing new. Researchers will measure changes in balance, sleep…

This study tests whether adding magnesium vitamin B6 to usual treatment can reduce depression, anxiety, and stress in people experiencing their first episode of bipolar I disorder. Forty adults aged 18-50 will take either the supplement or a placebo three times daily for four wee…

This study from Stanford University tests whether two breathing techniques—cyclic sighing and box breathing—can lower anxiety, compared to hypnosis or listening to an audiobook about stress. Eighty adults will practice daily for 4 weeks and have their brain activity and heart rat…

This study tests a program called ACT Together for parents of children with disabilities. The program includes six online lessons and weekly phone coaching sessions with a trained therapist. It teaches skills to handle stress and difficult emotions. Researchers want to see if the…

This study looks at whether using a weighted blanket during intravenous cancer treatment can help lower anxiety, stress, and depression, and improve comfort. About 152 adults with solid cancers who are starting their first IV therapy will be randomly assigned to receive either a …

This study tests whether a simple four-square breathing exercise done before breastfeeding can lower anxiety and improve well-being in mothers whose babies are in the neonatal intensive care unit (NICU). About 70 mothers will be split into two groups: one does the breathing exerc…

This study tests whether using virtual reality (VR) goggles during a colposcopy can lower women's anxiety, stress, and pain. About 60 women scheduled for the procedure will either receive standard care or wear a VR headset showing calming content. The goal is to see if this simpl…

This study tests whether listening to live or recorded music before neurosurgery can lower stress, improve mood, and reduce pain. Researchers will measure changes in vital signs, stress hormones, and how patients feel using questionnaires. The goal is to find a simple, drug-free …

This study tests two new online programs designed to help stressed adults feel better and more spiritually connected. About 44 people will take part, either in a live weekly class or a self-paced program. Researchers will use questionnaires, interviews, and brain scans to see wha…

This study tests whether an 8-week program of yoga or values clarification can help parents of children with special needs better manage stress and emotions. Parents are randomly assigned to a yoga group, a values clarification group, or a control group. The goal is to see if the…

This study is testing whether a daily prebiotic fiber powder can reduce stress in healthy adults with mild to severe stress. Over 12 weeks, 120 participants will take either the fiber blend or a placebo. Researchers will measure stress levels, mood, and gut health changes.

This pilot study looks at whether an 8-week stress reduction program can reduce inflammation in the arteries of adults aged 30-65 who feel stressed. Researchers will use special PET scans to measure changes in artery inflammation before and after the program. The goal is to see i…

This study tests whether a 4-week mindfulness meditation program can improve sleep quality, reduce stress, and ease symptoms in people receiving hemodialysis. Fifty adults on dialysis will either get meditation plus usual care or usual care alone. Researchers will measure changes…

This study tests whether a one-week smartphone training program can help unpaid caregivers of people with Alzheimer's disease better manage their emotions. Participants will be randomly assigned to learn one of two emotion-regulation techniques (distancing or reinterpretation) or…

This study tests whether Reiki, a gentle hands-on relaxation therapy, can help adults with cancer who feel very tired from immunotherapy. Twelve participants will either receive six weekly Reiki sessions right away or after a waiting period. Researchers will measure changes in fa…

This study looks at whether giving parents of children with chronic conditions a mental health questionnaire during clinic visits is practical and helpful. About 100 parents will fill out the survey and receive a list of support services. Researchers will follow up at 3 and 6 mon…

This study is testing whether an online, self-guided dialectical behavior therapy (DBT) course is practical and helpful for adults with mild-to-moderate depression or anxiety. Up to 40 participants will take the 8-week course, which teaches skills like mindfulness and emotion reg…

This pilot study tests whether trained community health workers (promotoras) can help Latinx and Native American adults with moderate to high stress access mental health services and feel better. About 80 participants will be split into two groups: one gets the navigator support,…

This study tests whether a daily nasal spray containing oxytocin, a natural hormone, can lower stress and improve quality of life in female family caregivers of people with dementia. About 32 women aged 50 and older who provide unpaid care will receive either a low or high dose o…

This study tests whether a tonic called Feel Free Classic can help healthy adults feel less stressed. About 165 people will take either the tonic or a placebo for 29 days. Researchers will measure stress levels and how the body processes the tonic's ingredients.

This study looks at whether a specific breathing technique called SKY breath meditation can help college students feel less stressed and anxious. About 53 students will be split into two groups: one learns the breathing method, the other does general yoga. Over 8 weeks, researche…

This study tests whether a daily 30-minute mindfulness practice using Tao Calligraphy (tracing lines with fingers) and Tao Song (listening, singing, or chanting) can lower stress, increase social connectedness, and boost peace of mind. Fifty adults will be randomly assigned to ei…

This study tests whether inhaling lavender essential oil for four weeks can reduce anxiety, stress, and depression in women waiting for IVF treatment. 120 women will be split into three groups: one using real lavender oil, one using a placebo scent, and one receiving no scent. Th…

This study tests whether taking a daily postbiotic supplement called Humiome® Post LB for three months can lower stress levels in adults aged 50 to 75. About 200 participants in France will either receive the supplement or a placebo, and their stress will be measured using a stan…

This study tests whether natural supplements like lavender oil, PEA, and OEA can help adults with moderate stress and sleep problems. About 240 participants will take a daily capsule for 8 weeks, comparing the supplements to a placebo. The goal is to see if these natural options …

This study tests whether a 6-week music program—including drumming and rhythm exercises—can reduce stress, anxiety, depression, and chronic pain in adults living in rural residential care facilities. Sixty participants will attend weekly hour-long sessions and complete surveys be…

This study aims to see if college students can effectively deliver cognitive-behavioral therapy (CBT) to high school students in rural Pennsylvania to reduce symptoms of depression, anxiety, and stress. About 40 teens aged 13-18 with mild to moderate symptoms will participate. Th…

This study looks at whether doing yoga during pregnancy can lower stress, improve sleep, and enhance sexual quality of life. Researchers will compare 35 pregnant women who practice yoga with 35 who do not. All participants are in their third trimester and must be able to read Tur…

This study explores whether virtual reality nature scenes and special sound patterns (binaural beats) can help healthy adults feel less stressed. 52 participants will attend a single 30-minute session, with some using VR or listening to sounds, while others serve as a control gro…

This study tests whether taking a daily prebiotic fiber blend for 12 weeks can lower stress levels in healthy adults who feel mild to severe stress. Participants will take either the fiber powder or a placebo and report their stress, mood, and anxiety. The goal is to see if feedi…

This study tests a mobile app called Blueprint that teaches coping skills to people who survived a serious illness in the ICU. Many survivors face anxiety, depression, and PTSD, but mental health care is hard to access. The app aims to help them manage these symptoms on their own…

This study tests whether personalized music playlists can reduce stress, anxiety, and depression in adults. 2,000 participants will either receive music designed to match and gradually shift their mood, or no music. The goal is to see if this simple, non-invasive approach can imp…

This study is testing whether a daily supplement called AGZ can help adults aged 25-59 who have trouble sleeping feel more relaxed in the evening, sleep better, and have more energy in the morning. About 300 people will take AGZ or a placebo for 30 days and answer questionnaires …

This study looks at whether a technique that combines brain training (neurofeedback) with mindfulness can lower anxiety and stress in nursing students and improve their grades. About 36 students from the University of Salamanca will take part. The goal is to see if this approach …

This study looks at whether swaddling (wrapping snugly) or nesting (creating a cozy boundary) can lower pain and stress in newborns who need breathing support. About 100 babies born after 35 weeks will be watched for heart rate, oxygen levels, and stress signs. A painless saliva …

This study tests whether wearing a virtual reality headset with calming scenes can reduce anxiety and stress during a cesarean section as well as a sedative drug called dexmedetomidine. Fifty-two women having planned C-sections will be randomly assigned to receive either the VR h…

This study tests whether using a virtual reality headset (REALICA) can lower pain and anxiety in people undergoing common urology procedures like prostate biopsy, cystoscopy, or circumcision. About 56 adults having these procedures for the first time will use the VR device during…

This study tests a two-week smartphone program designed to help people who struggle to feel pleasure (anhedonia) and also have high depression, anxiety, or stress. Participants do three short audio-guided exercises each day, focusing on gratitude, savoring positive moments, and f…

This study tests whether a nutritional supplement called 'Think Tank' can improve thinking and memory in middle-aged women after they experience stress. Forty healthy women aged 40-60 will take either the supplement or a placebo and then complete cognitive tests. The goal is to s…

This study tests a mobile app program called PRISM to help teens and young adults (ages 12-25) who have finished cancer treatment manage stress and build resilience. Participants will use the app to learn skills to cope with difficult situations. The goal is to see which version …

This study is testing whether a wrist-worn device called the WAVwatch 2.0, which plays calming sound frequencies, can help reduce stress and anxiety in adults. Researchers will recruit 100 participants and measure changes in stress, anxiety, and life satisfaction using standard q…

This study looks at whether eating nuts can help reduce symptoms of depression, anxiety, and stress, and improve memory and thinking skills in young adults. Researchers will enroll 135 university students aged 18 to 25 and measure changes in mood, cognitive function, and a brain-…

This study tests a 10-week program called SOULFOOD that combines mind-body techniques, nutrition advice, and relaxation exercises to help healthcare workers at University Medicine Essen build resilience and reduce burnout. About 252 employees with moderate stress levels will part…

This study tests a free 6-week online coaching program for NSU undergraduate students. The program aims to reduce anxiety, depression, and stress while improving quality of life and coping skills. About 160 students will participate, and the study measures changes using standard …

This study tests a culturally and language-adapted internet-based cognitive behavioral therapy (i-CBT) for Farsi/Dari-speaking youth migrants and refugees aged 15-29. The goal is to reduce symptoms of common mental health problems like anxiety, depression, and stress. Participant…

This study tests whether taking L-tyrosine, a natural supplement, can help lower stress in adults having outpatient hernia surgery. About 150 participants will receive either L-tyrosine or a placebo before surgery, and their anxiety levels will be measured. The goal is to find a …

This study tests whether a music therapy approach called therapeutic songwriting can improve mental health and social connections in university students who feel depressed, anxious, or stressed. Twenty participants will be randomly assigned to either four individual songwriting s…

This study tests whether a smartphone app that prompts physical activity can help adults with moderate depression feel better. Fifty participants will either use the app for four weeks or have their symptoms monitored without the app. Researchers will measure changes in depressiv…

This study tests whether the JoyPop app can help 110 Canadian youth aged 12-17 better manage their emotions while on a waitlist for mental health services. Participants use the app at least twice daily alongside usual care. The goal is to see if the app improves emotion regulatio…

This study tests whether the JoyPop app can help 18-25 year olds in Northwestern Ontario better manage their emotions and reduce stress while they wait for mental health services. Participants will use the app at least twice daily and be compared to those receiving usual care. Th…

This study tests whether a 9-step mindset management program called Organic Conceptions can reduce stress in women struggling with infertility. About 66 new patients at a fertility clinic will either take the program or serve as a control group. Researchers will measure stress le…

This study tests a program called RiSE that helps African American women cope with race-based stress. Researchers want to see if it improves well-being, reduces inflammation, and changes DNA markers. 300 post-menopausal women aged 50-75 with heart or metabolic risk factors will j…

This study tests whether the JoyPop app can help Indigenous youth aged 18-25 in Northwestern Ontario manage their emotions and reduce stress while they wait for mental health services. Participants will use the app at least twice daily and be compared to those receiving usual car…

This early-stage study at Johns Hopkins is testing whether cannabidiol (CBD) can reduce stress and nicotine withdrawal symptoms in people who smoke. Ninety healthy smokers will receive CBD and then be exposed to stress while researchers measure their mood, heart rate, and stress …

This study looks at how negative emotions like stress, pain, and frustration change the way people make decisions. Healthy adults aged 18 to 55 will experience different emotional triggers—such as heat, cold, or math problems—and then perform computer tasks while their brain acti…

This research study follows 500 adolescents with type 2 diabetes to understand why some develop kidney problems. Researchers are looking at biological factors like blood sugar and blood pressure, as well as psychological and social factors such as stress, mental health, and pover…

This study looks at whether patients who feel more stressed before shoulder surgery for rotator cuff problems have a harder recovery. Researchers will measure stress levels in 100 adults using a questionnaire before their operation. The goal is to see if high stress is linked to …

This study tracks 30 eye doctors and residents in France to see how working up to 60 hours straight affects their stress levels, heart rate, and surgical skills. Researchers will measure heart rate variability, saliva stress markers, and sleep quality. The goal is to understand i…

This study looks at whether being more forgiving and holding less resentment can improve quality of life for people living with HIV. Researchers will follow 206 participants at a French hospital, measuring their tendency to forgive and their well-being. The goal is to see if forg…

This study looks at how stress and social support might influence preterm birth in 200 pregnant women, especially among Black and Hispanic women who face higher risks. Researchers will measure stress levels, immune responses, and cellular energy (mitochondria) to understand why s…

This study looks at how sleep problems and stress can trigger migraines in adults. Participants wear a WHOOP band to track sleep and body signals, and answer daily questions via a smartphone app. The goal is to find personal patterns and give tailored advice to reduce migraine at…

This study looks at how stress impacts pain, hormone levels, and mood in 120 people with and without HIV, cannabis use disorder, and depression. Participants will complete two sessions of a pain stress task and provide blood samples to measure cortisol and other stress hormones. …

This study looks at whether women with a normal BMI but higher body fat have hidden blood vessel problems. Researchers will measure how their blood vessels react after a fatty meal and a stressful task. The goal is to understand if body composition matters more than weight for he…

This study looks at how a brief full-body cold-water bath, compared to warm water, changes the way people make decisions, their mood, and body signals like heart rate and stress hormones. Forty healthy adults aged 18-40 will take part. The goal is to understand if cold exposure c…

This study tests whether using audio and video recordings from an Operating Room Black Box during team debriefings helps reduce stress and improve teamwork among operating room staff. About 135 healthcare workers from three hospitals will be split into two groups: one using stand…

This study looks at how nomophobia—the fear of being without your smartphone—relates to stress, body image, and food addiction in university students aged 18 to 30. Researchers will use questionnaires and body measurements to find connections. The goal is to better understand the…

This study looks at whether playing music, with or without a parent's voice, can lower stress and help brain development in very premature babies. About 243 infants born between 24 and 30 weeks will be randomly assigned to hear music, music plus parent voice, or standard care. Re…

This study is testing whether a smartphone app can help firefighters improve their sleep, reduce stress, and boost thinking skills. About 50 firefighters will use the app and report how well it works. The goal is to see if the program is easy to use and helpful for real-life fire…

This study looks at whether an 8-week stress reduction program can lower inflammation in the arteries of people with stable heart disease. About 36 adults who feel stressed will take part. Researchers will use special PET/MRI scans to measure changes in artery and brain activity …

This study tests a program called FRAME that helps heart failure patients discuss stress, anxiety, and depression with their doctors and loved ones. About 7,300 patients in Ontario, Canada will take surveys before and after using the tool. The goal is to see if the program makes …

This study tests whether a 10-session parenting program called Attachment and Biobehavioral Catch-up (ABC) can reduce stress-related biomarkers in children aged 2 to 3.5 years who have experienced early adversity. About 150 caregiver-child pairs will be randomly assigned to recei…

This study looks at how acute stress affects the brain's energy metabolism and connectivity. Sixty-eight healthy volunteers will undergo brain scans while performing math tasks designed to induce stress. The goal is to understand individual differences in stress responses, which …

This study looks at why depression and heart disease often occur together in women going through menopause. Researchers will measure stress-related chemicals and heart rate in 30 women aged 44-55. The goal is to find clues that could lead to better ways to reduce heart disease ri…

This study looks at how cannabidiol (CBD) influences stress in 160 people aged 18-25 who experienced early life trauma. Participants receive either CBD or a placebo, then undergo brain scans and stress tests. The goal is to understand the brain and hormone changes behind CBD's st…

This study is looking at how lifestyle choices like diet, exercise, stress, and sleep relate to heart health measures such as blood pressure and cholesterol. Researchers will ask 100 adults and young people to fill out a questionnaire about their habits. The goal is to better und…

This study tests a training program called ASCEND, developed by the World Health Organization, for supervisors in Dutch small and medium-sized businesses. The goal is to help supervisors better support their employees' mental health, reduce stigma, and improve workplace well-bein…

This study tests whether a 14-day mobile diary is a practical way to measure daily stress and thinking (cognitive) changes in breast cancer survivors. Researchers will enroll 30 racially diverse women aged 40 and older who are at least five years past diagnosis. Participants comp…

This study looks at how stress changes the way opioid painkillers work in people with chronic back pain. Researchers will give participants oxycodone, a pain blocker, or a placebo in a lab setting to measure pain relief and drug liking. The goal is to understand why some people m…

This study looks at how adding chia seeds (a fiber source) to your diet and dealing with stress can change the bacteria in your gut. About 60 healthy adults will take chia seeds for two months and provide stool and blood samples. The goal is to learn how lifestyle factors affect …

This study looks at how searching for health information online affects stress and emotional well-being in women going through infertility treatment. Researchers will survey about 200 women to understand their online search habits, stress levels, and overall mental health. The go…

This study looks at how stress during childhood can impact heart and blood vessel health later on. Researchers will measure heart function, blood vessel flexibility, and lung function in 120 participants aged 9-30. The goal is to understand early signs of disease so that future p…