Can stress make painkillers more risky? new study investigates

NCT ID NCT05142267

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 23 times

Summary

This study looks at how stress changes the way opioid pain medications work in people with chronic low back pain. Researchers will measure pain relief and drug liking under different conditions to understand why some people may be at higher risk for misusing these medications. The goal is to learn more about the body's natural pain-control systems and how stress might interfere with them.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37212, United States

    Contact

Conditions

Explore the condition pages connected to this study.