CBD's brain effects under the microscope for stress relief

NCT ID NCT07278505

Recruiting now Knowledge-focused Sponsor: Icahn School of Medicine at Mount Sinai Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how cannabidiol (CBD) influences stress in 160 people aged 18-25 who experienced early life trauma. Participants receive either CBD or a placebo, then undergo brain scans and stress tests. The goal is to understand the brain and hormone changes behind CBD's stress effects, not to test it as a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cannabidiol (CBD)
What this could lead to: If successful, this study could clarify how CBD affects stress in people with early trauma, potentially guiding future stress treatments.
What could go wrong: This is an early-phase study focused on understanding mechanisms, not proving treatment effectiveness. Results may not lead to a new therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EARLY LIFE ADVERSITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

anxiety disorder injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EARLY LIFE ADVERSITY STRESS TRAUMA

Contacts and locations

Locations

Ichan School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.