Can early blood transfusions save more trauma victims?

NCT ID NCT05573841

Completed Knowledge-focused Sponsor: Karolinska University Hospital Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This study looks at trauma patients with severe bleeding to understand how early blood transfusions affect their chances of survival and blood clotting. Researchers will compare patients who receive a transfusion within two hours of arrival to those who do not, and also examine the impact of giving transfusions before reaching the hospital. The goal is to learn more about the best ways to treat major bleeding after trauma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Blood transfusion (erythrocytes, plasma, or whole blood)
What this could lead to: If successful, this could help refine transfusion protocols for trauma patients, potentially improving survival and reducing bleeding complications.
What could go wrong: As an observational study, it cannot prove cause and effect. Results may be influenced by differences in patient care and may not apply to other trauma centers.

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Conditions

The condition(s) this trial relates to.

Hemorrhage injury Shock, Traumatic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE COAGULOPATHY HEMORRHAGE SHOCK, TRAUMATIC TRAUMA

Contacts and locations

Locations

Karolinska University Hospital

Stockholm, 16771, Sweden

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