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A facelift without the bruising? tranexamic acid put to the test.

NCT ID NCT06345833

Disease control Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial tests whether applying tranexamic acid (TXA) directly to the face during facelift surgery can reduce bleeding and bruising better than a placebo. TXA is a medicine that helps blood clots stay intact, and it is already used intravenously for heavy bleeding. Here, it is applied either as an injection mixed with local anesthetic, as a soaked pad held on the skin, or both. Each participant receives TXA on one side of the face and saline on the other, so the comparison is within the same person. The study includes adults who are already scheduled for a facelift and are healthy enough for surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tranexamic acid (TXA) applied topically or locally during facelift surgery
What this could lead to
If effective, topical or local TXA could become a standard way to reduce bleeding and bruising after facelift surgery without the risks of intravenous use.
What could go wrong
This is a very early-phase trial with a small number of participants. It is testing multiple application methods, so it may not identify a clear winner. Although TXA is generally safe, rare allergic reactions or local side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Started

Jul 2024

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Eligible participants will consist of all regular clinic patients who elect and are deemed fit by the surgeon to undergo facelift surgery, including patients undergoing ancillary procedures * age 18 and older * English speaking. Exclusion Criteria: * younger than 18 * previously had an adverse reaction to tranexamic acid * non-English speaking * patients who elect not to participate or withdraw from the study.

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Conditions

The condition(s) this trial relates to.

hemophilia hemophilia A Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Facelift surgery Hemophilia Hemorrhage

Contacts and locations

Locations

  • University of Minnesota

    Minneapolis, Minnesota, 55414, United States

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