Ultrasound may reveal the true staying power of facial fat grafts
NCT ID NCT07805889
First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time
Summary
Facelift surgery repositions facial tissues but does not restore all lost volume. Surgeons often add the patient's own fat during the same operation to fill out the face, yet how much of that fat remains after a year is not well measured. This study follows 400 adults aged 18 to 65 who are scheduled for a facelift with fat grafting. Researchers use ultrasound scans at one month and one year after surgery to measure how much grafted fat persists and how the facial tissue changes over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Facelift surgery combined with facial fat grafting using the patient's own fat (macrofat)
- What this could lead to
- If successful, this could help surgeons know which fat grafting techniques lead to longer-lasting results, improving outcomes for facelift patients.
- What could go wrong
- This is an observational study, not a test of a new treatment. It will not prove which technique is best, and results may vary due to individual healing and measurement differences.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults undergoing elective facelift surgery for facial aging in whom autologous facial macrofat grafting is planned as part of the operative protocol.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 65 years. * Scheduled for elective facelift surgery with facial autologous macrofat grafting specified before enrollment. * Ability to undergo standardized facial ultrasound at baseline, postoperative month 1, and postoperative month 12. * Capacity to provide written informed consent and comply with follow-up visits. Exclusion Criteria: * Prior facial fat grafting within 24 months before enrollment. * Active facial infection, uncontrolled inflammatory skin disease, or open facial wound. * Known lipodystrophy or systemic disease expected to substantially alter facial fat distribution during follow-up. * Planned major weight-loss intervention or anticipated body-weight change greater than 10% during follow-up. * Pregnancy or breastfeeding at enrollment. * Inability to obtain technically adequate baseline ultrasound measurements in the predefined facial zones.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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NS Plastic surgery
RECRUITINGBarranquilla, Colombia
Contact Email: •••••@•••••
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