HEMOPHILIA

This study is testing a blood clotting treatment called prothrombin complex concentrate (PCC) for people with hemophilia A who have developed 'inhibitors' that make standard treatments ineffective. The research aims to see how well PCC controls bleeding episodes and how safe it i…

This study is testing a drug called fitusiran to see if it can safely and effectively prevent bleeding episodes in young boys with severe hemophilia A or B. About 85 boys aged 1 to under 12 will receive the drug for up to 3 years. The main goal is to see if fitusiran reduces the …

This study is testing whether an experimental injection called STSP-0601 can safely and effectively stop bleeding episodes in people with hemophilia A or B who have developed inhibitors. The trial will enroll 32 adults who experience frequent bleeding episodes to see how well the…

This study is testing whether a medication called Bevacizumab, injected directly into an inflamed joint, can reduce the frequency of painful bleeding episodes in people with hemophilia. The treatment aims to interrupt the cycle of inflammation and bleeding that damages joints ove…

This study aims to create a reliable laboratory test to measure how well new hemophilia treatments called anti-TFPI antibodies are working. Researchers will test blood samples from 11 adult men with severe hemophilia who are taking these new medications. The goal is to develop a …

This study aims to collect long-term safety and effectiveness data on treatments for various non-cancerous blood disorders, including hemophilia, von Willebrand disease, and platelet disorders. It will follow up to 3,000 participants for at least 15 years to see how newer, FDA-ap…

This study is collecting information about how patients with blood cancers and disorders respond to stem cell transplants in the high-altitude Tibetan region. Researchers are enrolling 1000 patients and their donors to track treatment patterns, recovery times, survival rates, and…

This study aims to gather detailed information on many different blood diseases in China, including cancers like leukemia and lymphoma, and conditions like hemophilia. It will follow 2,300 patients to learn how common these diseases are, what treatments patients receive, how well…

This study aims to find better ways to monitor the effectiveness of treatments for hemophilia patients who have developed inhibitors, which make standard treatments less effective. Researchers will test new blood analysis methods on 20 patients over two years to see if these test…