New blood test could improve bleeding control for hemophilia patients

NCT ID NCT07101926

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to create a reliable lab test to monitor how well anti-TFPI antibodies work in people with severe hemophilia. Researchers will take a single blood sample from 11 patients already on anti-TFPI therapy and test it in the lab. The goal is to better predict and manage bleeding, especially during surgery or severe bleeds.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could provide a reliable lab test to help doctors manage bleeding and surgery in hemophilia patients on anti-TFPI therapy.
What could go wrong
This is a very small, early-stage study (11 people) focused on developing a lab test, not testing a treatment. The test may not prove useful in real-world settings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre de Référence Hémophilie et autres déficits rares en protéine de la coagulationCentre de Traitemendes Hémophiles F. Josso

    NOT_YET_RECRUITING

    Paris, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Groupement hospitalier Est Hôpital Cardilogique Service d'hémostase clinique

    RECRUITING

    Bron, 69677, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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