Can a video call replace the clinic for hemophilia pain relief?
NCT ID NCT07682519
First seen Jul 06, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This study tests whether a 6-week online rehabilitation program—combining pain education and exercise—works as well as in-person sessions for adults with hemophilia who have chronic joint pain. Participants are randomly assigned to either telerehabilitation or face-to-face care. The goal is to see if the online approach can provide similar pain relief and improve access to care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Multimodal telerehabilitation (pain neuroscience education and therapeutic exercise)
- What this could lead to
- If successful, this could show that online rehabilitation is a viable alternative to in-person care, making treatment more accessible for people with hemophilia and chronic pain.
- What could go wrong
- This is a small, early-stage trial with only 24 participants, so results may not apply broadly. The non-inferiority design means it aims to show telerehab is not worse than face-to-face, not necessarily better.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Male adults aged 18 to 60 years. Diagnosis of hemophilia A or hemophilia B. Chronic pain, defined as pain occurring every day for at least 3 months or on at least half of the days during the previous 6 months. Pain involving the elbow, knee, or ankle. Receiving prophylactic clotting factor replacement therapy at least three times per week. Current medical referral for physical therapy. Residence in the Metropolitan Region of Chile. Ability to understand study procedures and provide written informed consent. Exclusion Criteria: Inability to understand study instructions or provide written informed consent. Neurological disorders affecting the central nervous system (e.g., stroke). Current participation in alternative therapies for pain management. Previous participation in a pain neuroscience education program. Orthopedic surgery or major musculoskeletal trauma within the previous 12 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Physical Therapy, Faculty of Medicine, University of Chile
RECRUITINGSantiago, Santiago Metropolitan, 80002, Chile
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