Scientists zap brains to unlock anxiety secrets
NCT ID NCT07415772
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses a non-invasive brain stimulation technique called TMS to temporarily change activity in a brain region linked to anxiety. Researchers will use fMRI scans to see how this affects brain connections and anxiety-related startle responses. 140 adults with anxiety will receive either real or sham TMS. The goal is to understand how TMS might work to reduce anxiety, which could lead to better treatments in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcranial Magnetic Stimulation (TMS)
What this could lead to
If successful, this could reveal how TMS changes brain activity related to anxiety, pointing toward more effective, non-invasive treatments.
What could go wrong
This is an early mechanistic study, not a treatment trial. It may not lead directly to a therapy, and results may not apply to all anxiety patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104-6013, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••