ANXIETY

This study looks at whether combining medication with one-on-one cognitive behavioral therapy helps people with mental health disorders like anxiety, depression, bipolar disorder, and schizophrenia. 107 adults aged 18-65 with an IQ of 80 or higher took part. The goal is to see if…

This study looks at the best ways to prevent anxiety and depression in older Latino adults (age 60+) who have mild symptoms but not a full disorder. About 240 participants will join either a health promotion program or a healthy lifestyles education class. Researchers will track …

This study tests whether a workshop led by fellow firefighters can help prevent PTSD, depression, anxiety, and alcohol problems in new firefighter trainees. About 480 recruits will take part during their academy training. They will either receive the emotion-regulation workshop o…

This study tests whether gentle sound waves aimed at the brain can help manage anxiety. 44 adults with high or low anxiety will receive either real or fake ultrasound before facing stressful tasks. Researchers measure startle reflexes and heart rate to see if the treatment calms …

This study tests whether using a virtual reality hypnosis headset (HypnoVR) can lower pain and anxiety during labor. About 70 women giving birth at hospitals in Tunis will use the headset, and researchers will measure their pain, anxiety, and satisfaction. The goal is to find a n…

This study tests whether group cognitive behavioral therapy can reduce both anxiety and insomnia in young people aged 12 to 20. About 171 teens with both conditions will attend therapy sessions focused on sleep or anxiety. The goal is to see if this talking therapy improves sympt…

This study tests a program called RESET, led by community health workers, to help older adults in Detroit improve their physical and mental well-being. About 456 African American adults aged 50 and older with symptoms like depression, anxiety, chronic pain, or loneliness will tak…

This study aimed to see if using virtual reality for guided mindfulness meditation could help adults with pain, stress, anxiety, or depression. Researchers planned to measure changes in mood and pain scores before and after VR sessions. However, the study was withdrawn before any…

This study looks at whether inhaling aromatherapy scents can help pregnant women manage pain, anxiety, and nausea during labor. About 128 women in labor will be invited to take part. Researchers will compare how they feel before and after using the scents to see if it makes a dif…

This study looks at whether a mindfulness program designed for pregnancy and parenting can help lower anxiety in expectant mothers. About 60 pregnant women with high worry levels will be randomly assigned to either the mindfulness class or a standard childbirth education class. R…

This study tests whether a device called CES (cranial electrotherapy stimulation) can safely reduce anxiety symptoms in 200 active-duty military members and their families. Participants receive either real CES or a sham (fake) device to see if the electrical stimulation truly hel…

This study tests whether a 5-week heart rate variability biofeedback program can reduce stress and anxiety in 50 dental students moving from classroom to clinic. Participants practice slow breathing while recalling a positive memory, guided by a device that gives real-time feedba…

This study aimed to see if having a parent appear on a screen during anesthesia induction could reduce children's anxiety as effectively as the sedative midazolam. It planned to enroll children aged 4-8 undergoing outpatient surgery. However, the study was withdrawn before any pa…

This study tests whether a 1-month meditation app can help juvenile justice officers and others working with court-involved youth feel less stressed, anxious, or burned out. About 57 adults who work directly with these youth will use the app and report how acceptable and helpful …

This study planned to compare three different nose sprays (dexmedetomidine, fentanyl, and midazolam) for reducing pain and anxiety in young children (ages 2-6) getting stitches in the emergency room. The goal was to see which spray worked best and was safest. However, the study w…

This study looks at whether laughter yoga can lower exam anxiety and improve feelings of spirituality in nursing students. About 36 students will take part in 8 laughter yoga sessions over 4 weeks, while a similar group does nothing extra. Researchers will compare anxiety and spi…

This study tests a therapy called FIRST, which uses five key principles to help youth aged 7 to 15 with anxiety, depression, trauma, or behavior problems. Researchers compare FIRST to usual care to see if it improves mental health and helps kids manage negative emotions. The stud…

This study tests whether watching a virtual reality (VR) video of an ECT session can reduce anxiety and improve understanding in people about to receive ECT for the first time. About 64 participants will be randomly assigned to either the VR experience or a standard talk with a p…

This study tests two medications, dexmedetomidine and tramadol, given before hemorrhoid surgery to see which one better reduces anxiety and pain. 90 adults undergoing the procedure will be randomly assigned to receive one of the drugs, and their anxiety levels, pain scores, and v…

This study looks at whether watching an immersive video before open-heart surgery can lower patients' anxiety and improve their recovery. About 200 adults scheduled for elective heart surgery will take part. Researchers will measure anxiety using questionnaires and vital signs be…

This study tests whether using a mindfulness app for 8 weeks can improve mental health in Korean immigrants aged 60 and older. Participants use the app 10-15 minutes daily and have weekly check-ins. The goal is to see if the app reduces stress, anxiety, and depression while boost…

This small pilot study is testing whether a type of talk therapy called Positive Affect Treatment (PAT) can help Spanish-speaking adults who feel low pleasure or interest (anhedonia) along with depression or anxiety. The therapy focuses on increasing positive emotions and reward …

This study tests whether an 8-week virtual music-based relaxation program can help reduce anxiety in adolescent and young adult cancer survivors aged 15-39. Participants will practice relaxation skills for 45 minutes each week. The goal is to see if the program is practical and h…

This study looks at whether laughter yoga or emotional freedom technique (EFT, a tapping therapy) can lower anxiety in pregnant women. About 120 women with moderate to high anxiety will be randomly assigned to one of these two methods or standard care. The goal is to see if these…

This study tests two non-invasive devices that stimulate the vagus nerve (one on the neck, one on the ear) to see which better reduces physical discomfort and health-related anxiety in people with Somatic Symptom Disorder. About 60 adults will try both devices in random order, ea…

This study tests whether a wearable patch that uses gentle vibrations can help people feel less stressed or anxious. About 150 adults aged 18 to 85 who already experience stress or anxiety will either get the active patch or a fake (sham) patch. They will report their feelings th…

This study is testing a 12-week group therapy program for adults with generalized anxiety disorder who have trouble dealing with uncertainty. The program uses cognitive-behavioral techniques to help participants manage worry and anxiety. About 12 to 20 people will take part, and …

This study looks at whether adding 10 grams of fibre to your daily diet for two weeks can improve mental wellbeing, including anxiety, stress, sleep, and mood. About 40 healthy adults aged 18 to 40 will take part. Researchers will measure changes using standard questionnaires bef…

This study looks at whether a 20-second hug from a family member right before surgery can help lower anxiety and pain afterward. About 160 adults having planned surgery will either hug or not hug their loved ones. Researchers will measure anxiety levels before surgery and pain sc…

This study tests a brief, acceptance-based behavioral therapy to improve mental health in 240 LGBTQ+ adults who have mild anxiety or depression. Participants either receive the therapy or continue their usual care. The goal is to see if this short intervention can reduce symptoms…

This study tests a small vibrating device (like a buzzer) to see if it can reduce pain and anxiety during needle sticks. Researchers will compare how children and adults feel with and without the device. The goal is to find a simple, drug-free way to make procedures like blood dr…

This study tests a culturally tailored mobile health program for 150 Black pregnant women to see if it reduces symptoms of depression, anxiety, and stress. Half of the participants receive the app, which teaches communication and self-advocacy skills and offers a support network.…

This study looks at an accelerated version of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain treatment, to see how many sessions work best for reducing depression and anxiety symptoms. About 70 adults with major depression will receive different doses o…

This study looks at whether kava, a plant used for relaxation, can safely reduce anxiety and stress in people who have finished cancer treatment. About 43 survivors of breast, gynecologic, lung, or head/neck cancer will take either kava or a placebo for 14 days, then switch after…

This study looks at whether a single art therapy session can improve mood and reduce symptoms like pain and anxiety in adults receiving palliative care. Twenty patients in a Canadian hospital will complete short questionnaires before and after a 30-60 minute art session. The goal…

This study tests a therapy program delivered remotely via technology for people with mild cognitive impairment or dementia who also have anxiety. The goal is to see if this approach can reduce anxiety and improve quality of life. The study involves 70 participants and uses a rand…

This study aims to help mothers of babies in intensive care cope with depression, anxiety, and stress while also providing resources for food, rent, and utilities. About 200 caregivers of infants up to 6 months old will receive emotional support and referrals to community service…

This study tests a new way to treat anxiety by combining a gentle brain stimulation technique (tDCS) with meditation in virtual reality. Over two weeks, 52 adults with generalized anxiety disorder will receive 12 sessions of either real or fake tDCS while meditating in a calming …

This study tests a 12-session group therapy program designed to help active duty military personnel who are having suicidal thoughts or have recently attempted suicide. The therapy teaches coping skills and emotion regulation techniques to reduce suicide risk. Researchers will co…

This study looks at whether using a stress ball during a prostate biopsy can help lower anxiety and pain. About 66 adults having their first prostate biopsy will be asked to squeeze a stress ball during the procedure. Researchers will measure pain, anxiety, and vital signs to see…

This study is testing whether a relaxation technology called Cereset can help nurses on a hospital unit feel less stressed, anxious, and sleep better. About 40 nurses will use the device, which uses gentle sounds to guide the brain into a calm state. The goal is to see if this im…

This study explores whether a functional food—a fruit compote made with maqui berry, prebiotics, and probiotics—can reduce anxiety and inflammation in 30 university students aged 18-40. Participants eat the compote as part of their normal diet, and researchers measure changes in …

This study looks at whether exercise can ease anxiety symptoms in adults who don't currently exercise. 111 people with anxiety disorders will do either low or high intensity workouts for 8 weeks. Researchers will track changes in anxiety sensitivity and overall functioning, and f…

This study tests whether watching calming nature videos with virtual reality (VR) glasses can lower pain and anxiety in people recovering from colorectal surgery. Sixty adults will be split into two groups: one group uses VR glasses for 10-15 minutes before and after surgery, whi…

This study tests a telephone-based, computer-aided care program for adults with depression, anxiety, or risky drinking. Participants receive extra support from a Mental Health Technician who helps their primary care provider manage treatment. The goal is to see if this approach r…

This study aimed to see if a sphenopalatine ganglion (SPG) block—a numbing shot inside the nose—could reduce anxiety in adults at electronic dance music festivals. Participants would have received either lidocaine or a saltwater placebo. However, the study was withdrawn before en…

This early-stage study tested a high-CBD, low-THC liquid spray for 8 weeks in 12 older adults with mild cognitive impairment or mild-to-moderate Alzheimer's who had significant anxiety or agitation. The goal was to see if it could reduce these behavioral symptoms safely. The stud…

This study looks at whether two Akashic Records sessions (a spiritual practice exploring past life patterns) can help reduce stress, anxiety, and depression in adults. About 117 participants will attend private video sessions and complete surveys over two months. The goal is to s…

This study tests whether a 4-month anti-inflammatory diet can reduce symptoms of anxiety and depression in 60 adults. Participants will be assigned to either the special diet or their usual eating habits. Researchers will also use AI to analyze speech and facial expressions to se…

This pilot study explores whether laughter yoga can reduce depression and anxiety in children aged 8-12 with autism spectrum disorder, and lower parenting stress in their parents. About 66 families will either join laughter yoga sessions or be placed on a waitlist. The study focu…

This study tests a new type of group therapy called Cognitive Evolutionary Therapy for people with mild to severe depression and anxiety. 64 adults will either receive two full days of therapy or be placed on a waitlist. Researchers will measure changes in mood, sleep, and stress…

This study tests whether a device that gently stimulates a nerve in the ear (TAVNS) can reduce anxiety and distress in healthcare workers. About 90 participants will use the device and some will also have brain scans to see how it affects brain activity. The goal is to find a sim…

This study tests a 7-week group program led by trained peers (not doctors) to help cancer survivors reduce anxiety and depression after finishing curative treatment. 234 adults in Denmark who completed cancer treatment within the past year and have mild-to-moderate symptoms are t…

This study tests whether adding ear acupressure (sticking tiny seeds on ear points) to standard IVF care can help women aged 20-45 feel less anxious, sleep better, and possibly improve pregnancy rates. Participants will either receive standard medication alone or standard medicat…

This study looks at whether cancer patients can use meditation on their own to reduce anxiety and depression. About 35 patients will try techniques like deep breathing or movement for two weeks. The goal is to see if this approach is practical and helps improve emotional well-bei…

This study tests whether Emotional Resolution (EmRes) therapy can reduce anxiety in 150 healthcare workers. Participants will either receive EmRes or practice mindfulness-based gratitude. The goal is to see if EmRes leads to greater anxiety relief, measured by a standard anxiety …

This early-stage study tests a smartphone app called NEAT-O that teaches coping skills to people with opioid use disorder who also have anxiety or depression. About 15 adults currently in medication treatment for opioid use will try the app for a few weeks. Researchers will check…

This study looks at whether having a licensed counselor available can improve the mental well-being of medical residents. About 21 internal medicine residents will take part. Researchers will measure changes in well-being, depression, and anxiety to see if this support model help…

This study tests whether using a virtual reality headset during PICC or PICC-PORT placement can reduce anxiety and pain in cancer patients. About 120 adults will be randomly assigned to either receive VR plus standard care or standard care alone. The goal is to see if VR can impr…

This study looks at whether teaching progressive relaxation exercises and providing planned education can help menopausal women reduce their symptoms, stress, and anxiety. About 144 women going through menopause will participate. The goal is to see if these non-drug approaches im…

This study looks at whether watching a video or using acupressure can lower anxiety and pain in children having a tooth pulled. About 69 healthy kids aged 5-8 will take part. Their heart rate and self-reported fear and pain will be measured to see which method works best.

This study tests whether an internet-based cognitive therapy program, guided by a therapist, can reduce fear of cancer recurrence in colorectal cancer survivors. About 200 Danish adults who completed treatment for colorectal cancer without recurrence will participate. The program…

This study looks at whether spending time with a therapy dog can reduce anxiety and stress in graduate students. Thirty first-year grad students will have their pain sensitivity and stress hormone levels measured before and after interacting with a dog. The goal is to see if regu…

This study aimed to see if holistic pastoral counseling could help people manage stress at work and in daily life. It was designed for unmarried Alaska Medicaid recipients aged 22 and older who had internet access and a Bible. However, the study was withdrawn before any participa…

This study looks at how stuck or rigid thinking patterns change over time in 35 people getting residential treatment for substance use disorders, anxiety, or depression. Participants fill out weekly surveys about their thoughts and behaviors, and researchers also analyze their th…

This study looks at whether using social media apps too much can make anxiety worse. Researchers will track changes in anxiety and depression in 100 adults who use smartphones. The goal is to find healthier ways to use phones without harming mental health.

This study looks at whether a video-based smartphone program can help reduce stigma and medical mistrust among Black adults (ages 18-45) who have depression or anxiety but haven't seen a mental health professional in the past year. About 90 participants will use the app and repor…

This study tests a short, one-time online mental health program for 80 people waiting for psychological treatment. Participants will try one of two versions of the program or a control activity and fill out questionnaires over 5 weeks. The goal is to see if the program is easy to…

This study follows 100 people having jaw surgery to correct bite problems or facial imbalances. Researchers will measure changes in jaw joint structure, chewing muscle strength, emotional responses, anxiety, sleep quality, and facial pain before and up to 6 months after surgery. …

This study follows 2,000 Stanford undergraduates over their college years to understand how social connections, daily moods, and brain activity relate to anxiety, depression, loneliness, and stress. Researchers use surveys, smartphone check-ins, and brain scans to gather data. Th…

This study looks at whether certain brain waves in the prefrontal cortex can serve as a marker for social anxiety. Researchers will monitor the brain activity of 30 people with social anxiety disorder while they anticipate giving a speech. The goal is to better understand the bio…

This study was designed to see if a drug called LY-2940094 could protect healthy people from developing depression or anxiety after stress. Researchers planned to measure brain responses to rewards and fear using tasks and questionnaires. However, the study was withdrawn before a…

This study looks at 50 adults with sleep bruxism (teeth grinding during sleep) to understand how it affects sleep, pain, anxiety, and overall health. Researchers will measure brain waves during sleep, check blood markers, and look at genetic factors. The goal is to find better wa…

This study tests whether painting roofs with a special reflective coating can lower indoor temperatures and improve mental health. Researchers will compare 800 households in Ahmedabad, India, that either get the cool roof or not. They will measure depression, anxiety, and well-be…

This study looks at health records of about 100,000 people in Israel to see if viral infections like COVID-19 or Epstein-Barr increase the risk of developing mental health conditions such as depression, anxiety, bipolar disorder, or schizophrenia. It also examines whether infecti…

This study tests an 8-week school program called INSPIRE for Indonesian teens aged 13-15. The program aims to improve mental health knowledge, resilience, and reduce symptoms of depression and anxiety. About 680 teens and their parents will take part, with results measured right …

This pilot study is testing whether adults with acute psychiatric conditions like psychosis, anxiety, or depression can safely receive hospital-level care at home instead of in a hospital. Researchers are enrolling 41 participants to see how many people are eligible and willing t…

This study tests whether a nurse-led health coaching program helps women aged 45 to 64 in Hong Kong use medical services more wisely and feel more in control of their health. About 1,728 women will either receive the nurse coaching or general health advice. The goal is to see if …

This study tests a program for refugee families living in the U.S. It combines family group sessions with virtual teen mentoring to help reduce emotional and behavioral problems like PTSD, depression, and anxiety in teens. About 308 teens and their parents will take part. The goa…

This study planned to test whether scheduled video or audio calls could improve communication and reduce anxiety and depression for family members making medical decisions for hospitalized older adults with Alzheimer's or other cognitive impairments. The study was withdrawn befor…

This study interviews 18 physiotherapists to understand how they screen for anxiety and depression in patients with chronic neck, shoulder, or back pain. The goal is to identify what helps or hinders them from recognizing mental health issues and referring patients for care. The …