Could a common virus trigger mental illness? massive study investigates

NCT ID NCT07453420

Ongoing Knowledge-focused Sponsor: Shalvata Mental Health Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study uses health records from about 100,000 people in Israel to see if past viral infections (like Epstein-Barr, COVID-19, or herpes) increase the risk of developing mental illnesses such as depression, anxiety, bipolar disorder, or schizophrenia. It also looks at whether infections can cause relapses in people who already have a mental illness. Researchers will examine factors like age, sex, and social background that might make someone more vulnerable or resilient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify who is most at risk for mental illness after infections and point to protective factors.
What could go wrong: This is an observational study using existing data, so it cannot prove cause and effect. Results may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder bipolar disorder Infections major depressive disorder psychiatric disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY BIPOLAR DEPRESSION - MAJOR DEPRESSIVE DISORDER SCHIZOPHENIA DISORDER

Contacts and locations

Locations

University of Haifa

Haifa, Israel

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