Nose spray pain relief for kids: which works best?

NCT ID NCT05057689

Terminated Symptom relief Sponsor: Nationwide Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study planned to compare three different medications given as nose sprays to children aged 2 to 6 years who needed stitches for a cut. The goal was to see which one worked best for pain and anxiety during the procedure. However, the trial was withdrawn before any children were enrolled, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intranasal dexmedetomidine, intranasal fentanyl, intranasal midazolam
What this could lead to: If it had succeeded, this could have pointed toward a better way to manage pain and anxiety in young children during minor emergency procedures.
What could go wrong: The trial was withdrawn before enrolling any participants, so no results are available. It was also a small Phase 2 study, meaning even if completed, findings would need further confirmation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute stress disorder anxiety anxiety disorder Pain Stress Disorders, Traumatic, Acute

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE STRESS DISORDER ANXIETY PAIN

Contacts and locations

Locations

Arkansas Children's Hospital

Little Rock, Arkansas, 72202, United States

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