Magnetic pulses to the brain may calm anxiety in Parkinson's — a trial puts it to the test

NCT ID NCT06999330

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can reduce anxiety in people with Parkinson's disease. Anxiety affects up to 40% of people with Parkinson's, and standard medications often fall short or cause side effects. The study targets a specific brain region linked to anxiety and compares real TMS to a sham (placebo) treatment in 15 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
theta burst stimulation delivered via a transcranial magnetic stimulation (TMS) device
What this could lead to
If it works, this could point toward a non-drug treatment for anxiety in Parkinson's disease, improving quality of life without medication side effects.
What could go wrong
This is a very small, early feasibility study with only 15 participants, so results may not apply broadly. TMS can cause headache or scalp discomfort, and the sham group helps check for placebo effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • HealthPartners Neuroscience Center

    Saint Paul, Minnesota, 55130, United States

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