Healthpartners Institute

This study tests if axelopran, a drug used for opioid-induced constipation, can slow tumor growth in people with advanced breast, lung, pancreas, or prostate cancer. About 34 adults whose cancer has worsened after standard treatment will take axelopran daily for up to a year. Res…

This study tests a new device called Limpet, which uses gentle suction to keep the area around an ostomy clean and dry. About 92 adults who have had ileostomy surgery or have a high-output fistula will either get the Limpet or standard adhesive pouches. Researchers will check for…

This study tests two types of wound vacuum therapy for people with severe, flesh-eating infections. One method just uses suction, while the other also cleans the wound with a dilute bleach solution. Researchers want to see if the cleaning method leads to fewer hospital readmissio…

This study tests whether starting an accelerated shoulder rehabilitation program immediately after reverse total shoulder replacement leads to better pain relief and function than the standard rehab approach. About 74 people with shoulder osteoarthritis will be randomly assigned …

This study looks at whether adding psychological support to standard exercise rehab helps people aged 15-21 recover from ACL reconstruction surgery. About 60 participants will be split into two groups: one gets extra emotional support from specially trained physical therapists, t…

This study looks at whether light or moderate exercise is better for adults with myasthenia gravis, a condition that causes muscle weakness. Twenty participants will join a 12-week exercise program three times a week. The goal is to see which intensity is more doable and improves…

This early-stage study is checking if insulin nasal spray is safe for people with spinal cord injury. Up to 12 adults who had an injury at least 4 months ago will use the spray or a placebo daily for up to 24 days. Researchers will monitor side effects and see if virtual training…

This registry study is collecting real-world data from 1,000 adults with cancer who use cannabis. Participants use an app to track symptoms, cannabis use, and changes in other medications. The goal is to help patients and doctors make informed decisions about using cannabis for s…