Healthpartners Institute

This trial compares two approaches for a specific type of pelvic fracture (LC1) in people aged 60 and older. One group receives a minimally invasive surgery to place screws that stabilize the bone, while the other group gets pain management and physical therapy without surgery. T…

This study tests whether a 12-week adaptive exercise program can reduce chronic inflammation in people with spinal cord injury (SCI). Chronic inflammation is linked to heart and lung disease, the top causes of death in SCI. Twenty-four adults with SCI will be randomly assigned to…

This pilot study compares two imaging methods—ICG microangiography and conventional angiography—in 8 adults with severe frostbite. The goal is to see if the safer ICG dye test can accurately show damaged tissue, potentially replacing the standard angiogram that uses contrast dye …

This study tested a wearable system (a haptic module and insole device) designed to detect freezing of gait in people with Parkinson's disease and then trigger cues to help them start walking again. The study enrolled 31 participants and aimed to validate the device's performance…

This study looked at 8 adults with metastatic breast cancer who were starting the drug alpelisib. Alpelisib often causes high blood sugar, so researchers used a continuous glucose monitor (a small sensor worn on the arm) to track glucose levels day and night for at least 3 months…

This Phase 2 trial tested whether insulin sprayed into the nose is safe for people with Parkinson's disease. Over 3 weeks, 31 participants received either intranasal insulin or a placebo. Researchers monitored safety events like low blood sugar and weight loss, and also looked at…

This study tested whether acupuncture can improve quality of life and daily activities for people with myasthenia gravis, a condition that causes muscle weakness. Twenty-four adults received acupuncture twice a week for 12 weeks, with some starting immediately and others after a …

This large study looks back at medical records of over 36,000 mother-infant pairs to see if receiving the Tdap vaccine during pregnancy or shortly after birth is linked to infant growth, how often babies need doctor or emergency visits, and whether mothers start or continue breas…

This completed study tested a web-based tool called PedsBP CDS that helps doctors identify and manage high blood pressure in children aged 6-17. The tool was used in 45 primary care clinics across three rural states, involving over 41,000 youth. The goal was to see if the tool im…

This study tested a computer program that helps primary care doctors identify older adults who might have early memory loss or dementia. Over 3,200 patients aged 65 and older took part. The tool uses information from electronic health records to flag patients who may need further…

This study tested a computer tool called the Opioid Wizard that helps primary care doctors identify and treat patients with opioid use disorder. Over 10,000 patients from 30 clinics participated. The tool works within the electronic health record to provide tailored treatment rec…