Exercise may fight hidden inflammation in spinal cord injury

NCT ID NCT05376449

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 12-week adaptive exercise program can reduce chronic inflammation in people with spinal cord injury (SCI). Chronic inflammation is linked to heart and lung disease, the top causes of death in SCI. Twenty-four adults with SCI will be randomly assigned to start exercise right away or after a 12-week delay, and researchers will measure changes in inflammatory markers like C-reactive protein.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Adaptive exercise program (HealthPartners NeuroWell Exercise Program)

What this could lead to

If it works, this could point toward a simple, non-drug way to reduce inflammation and improve long-term health for people with spinal cord injury.

What could go wrong

This is a small, early study with only 24 participants, so results may not apply to everyone. Exercise may not reduce inflammation enough to make a real difference in disease risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • HealthPartners Neuroscience Center

    Saint Paul, Minnesota, 55130, United States