Exercise may fight hidden inflammation in spinal cord injury

NCT ID NCT05376449

Completed Disease control Sponsor: HealthPartners Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 12-week adaptive exercise program can reduce chronic inflammation in people with spinal cord injury (SCI). Chronic inflammation is linked to heart and lung disease, the top causes of death in SCI. Twenty-four adults with SCI will be randomly assigned to start exercise right away or after a 12-week delay, and researchers will measure changes in inflammatory markers like C-reactive protein.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Adaptive exercise program (HealthPartners NeuroWell Exercise Program)
What this could lead to: If it works, this could point toward a simple, non-drug way to reduce inflammation and improve long-term health for people with spinal cord injury.
What could go wrong: This is a small, early study with only 24 participants, so results may not apply to everyone. Exercise may not reduce inflammation enough to make a real difference in disease risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPINAL CORD INJURIES

Contacts and locations

Locations

HealthPartners Neuroscience Center

Saint Paul, Minnesota, 55130, United States

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