Testosterone may rebuild strength after spinal cord injury — trial puts it to the test
NCT ID NCT07742553
First seen Aug 03, 2026 · Last updated Aug 05, 2026 · Updated 2 times
Summary
This trial tests whether testosterone therapy can help men with spinal cord injury who have low testosterone and difficulty walking. The goal is to see if it increases muscle and bone in the legs, reduces body fat, and improves strength. Some participants also receive finasteride to see if blocking a stronger hormone affects the benefits. The study involves 300 veterans and compares testosterone with or without finasteride against placebos.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- testosterone cypionate with or without finasteride
- What this could lead to
- If effective, testosterone therapy could help men with spinal cord injury regain muscle and bone strength, reduce fat, and improve mobility and quality of life.
- What could go wrong
- This is an early-to-mid-stage trial, so results may not be conclusive. Testosterone can have side effects like prostate issues, and the added finasteride may not preserve benefits as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ENDOCRINE SYSTEM DISEASES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
James A. Haley Veterans' Hospital, Tampa, FL
Tampa, Florida, 33612, United States
-
James J. Peters VA Medical Center, Bronx, NY
The Bronx, New York, 10468-3904, United States
-
North Florida/South Georgia Veterans Health System, Gainesville, FL
Gainesville, Florida, 32608-1135, United States
-
Rocky Mountain Regional VA Medical Center, Aurora, CO
Aurora, Colorado, 80045-7211, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a 'Smart Bridge' in the spine help paralyzed patients walk again?
- Can lifestyle choices after a stroke extend life and prevent a second one?
- Strumming for the brain: could ukulele lessons sharpen minds in MS?
- Could music be medicine for the injured brain?
- Can whole blood beat component transfusions in trauma?
- Spinal zaps may steady blood pressure in spinal cord injury