Could a constipation drug slow cancer growth? new trial seeks answers

NCT ID NCT07354919

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if axelopran, a drug used for opioid-induced constipation, can slow tumor growth in people with advanced breast, lung, pancreas, or prostate cancer. About 34 adults whose cancer has worsened after standard treatment will take axelopran daily for up to a year. Researchers will check tumor response at 6 weeks and monitor safety and quality of life.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • HealthPartners Cancer Center at Regions Hospital

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

  • HealthPartners Frauenshuh Cancer Research Center

    RECRUITING

    Saint Louis Park, Minnesota, 55426, United States

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