Can a phone app and a coach help Spanish-Speaking patients beat depression?

NCT ID NCT05746767

ENROLLING_BY_INVITATION Symptom relief Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a digital cognitive behavioral therapy program (SilverCloud) for Spanish-speaking adults with depression or anxiety. 426 participants will either use the program on their own or get extra support from a peer coach via phone or messaging. The goal is to see if adding human support improves symptoms and access to care in primary care settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: digital cognitive behavioral therapy (SilverCloud platform) with or without peer supporter check-ins
What this could lead to: If successful, this could show that adding peer support to digital therapy improves depression and anxiety outcomes for Spanish-speaking patients in primary care.
What could go wrong: This is a relatively early implementation study, not a large late-phase trial. The intervention relies on internet access and tech literacy, which may limit generalizability. Results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION, ANXIETY

Contacts and locations

Locations

Castro-Mission Health Center

San Francisco, California, 94114, United States
Family and Community Medicine Mobile Health Clinic

Tucson, Arizona, 85711, United States
Payson Christian Clinic

Payson, Arizona, 85541, United States
Sandoval Regional Medical Center

Rio Rancho, New Mexico, 87144, United States
Silver Avenue Family Health Center

San Francisco, California, 94134, United States
Truman Health Clinic

Albuquerque, New Mexico, 87102, United States
UNM Southeast Heights Clinic

Albuquerque, New Mexico, 87108, United States
UNMH North Valley Clinic

Albuquerque, New Mexico, 87017, United States
University of California

Berkeley, California, 94720, United States
University of California

Irvine, California, 92697, United States
Zuckerberg San Francisco General

San Francisco, California, 94110, United States

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