Could CBD be the next frontier for anxiety relief?

NCT ID NCT06672666

Ongoing Symptom relief Sponsor: University of Florida Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study investigates whether a hemp-derived cannabidiol (CBD) extract can safely reduce anxiety and improve sleep in adults with moderate to severe anxiety. Over four weeks, participants take 50 to 150 mg of CBD daily, with doses adjusted based on tolerance. The trial tracks side effects, liver health, and changes in anxiety and sleep symptoms to determine the best dosing strategy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hemp-derived cannabidiol (CBD) extract
What this could lead to: If it works, this could point toward a natural, plant-based option for managing anxiety and sleep issues with fewer side effects than standard medications.
What could go wrong: This is a small, early-phase pilot study with only 30 participants. It is designed to test safety and dosing, not to prove effectiveness. CBD can cause side effects like drowsiness or liver issues, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder generalized anxiety disorder Parasomnias

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY GENERALIZED ANXIETY DISORDER SLEEP PROBLEMS

Contacts and locations

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Locations

University of Florida

Gainesville, Florida, 32611, United States

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