GENERALIZED ANXIETY DISORDER

This study is testing whether an oral medication called MM120 can help reduce symptoms of generalized anxiety disorder (GAD). About 375 adults with moderate to severe anxiety will take either MM120 or a placebo for 12 weeks, followed by a 40-week period where everyone may receive…

This study aims to improve access to effective therapy for children with anxiety and OCD by testing different delivery methods. It will compare weekly Cognitive Behavioral Therapy (CBT) delivered entirely in-person, entirely via telehealth video calls, or through a flexible mix o…

This study is developing and testing a new online therapy program for children and adolescents with anxiety disorders. Up to 48 young people, aged 8 to 18, will use the 12-week program to learn skills for managing their anxiety. Researchers will measure if the program reduces anx…

This study is testing whether a non-invasive brain stimulation technique can help reduce symptoms of Generalized Anxiety Disorder. Researchers are using a precise, GPS-like system to target a specific area of the brain thought to be involved in anxiety. Participants will receive …

This UCLA study is testing whether a gentle, focused ultrasound can help people with severe, treatment-resistant anxiety. The ultrasound targets a deep part of the brain called the amygdala, which is involved in fear and anxiety. Researchers will compare real ultrasound treatment…

This study is testing whether an oral medication called MM120 can help control symptoms of generalized anxiety disorder. It will involve 200 adults with moderate to severe anxiety who will take either the medication or a placebo for 12 weeks, followed by an optional 40-week exten…

This study is testing whether a new medication called ITI-1284 can help adults with moderate to severe generalized anxiety disorder (GAD) who haven't gotten enough relief from at least two standard anxiety treatments. About 570 participants will be randomly assigned to receive ei…

This study is testing whether a computer-delivered therapy program can help people who have both alcohol use disorder and an anxiety disorder. Researchers want to see if this accessible, online version of a proven therapy works as well as when delivered by a therapist. The goal i…

This study is testing whether a new drug called ITI-1284 can help adults with moderate-to-severe generalized anxiety disorder (GAD) who haven't gotten enough relief from their current standard medication. About 705 participants will take either the new drug at one of two doses or…

This study aims to find out if a simpler, two-step therapy model works as well as a more personalized model for treating anxiety in children and teens. Researchers will compare starting all kids with online therapy first versus assigning them to either online or in-person therapy…

This study is testing a new medication called crisugabalin to see if it can safely reduce anxiety symptoms better than a placebo or an existing drug. It involves 216 Chinese adults with generalized anxiety disorder. Participants are randomly assigned to receive either the new dru…

This study is testing if Swedish massage can help reduce symptoms of Generalized Anxiety Disorder (GAD) by changing how the brain works. Researchers will compare two groups: one receiving real massage and one receiving light touch, both twice a week for six weeks. They will use b…

This study aims to understand how mindfulness training helps people with generalized anxiety disorder by looking at changes in their brain activity. Researchers will compare an 8-week mindfulness program to a stress education program in 150 adults with anxiety, using brain scans …

This study aims to understand how stimulating different parts of the brain with magnetic pulses affects symptoms of several mental health conditions. Researchers will enroll 180 adults with depression, anxiety, OCD, or schizophrenia to receive non-invasive brain stimulation at ra…

This is a long-term observational study aiming to understand why medical students experience high rates of depression and anxiety. Researchers will follow up to 10,000 students over many years, comparing those in medical school to those who were not accepted. The goal is to ident…

This study aims to find out if a person's reaction to a safe, brief carbon dioxide (CO2) breathing test can predict whether they will not respond to a common and effective talk therapy called exposure therapy. Researchers will give the test to 600 adults with conditions like anxi…