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Can your genes guide better mental health meds? new trial aims to find out

NCT ID NCT05656469

Recruiting now Disease control Sponsor: Parnassia Groep Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using a person's genetic information to guide medication choices leads to better recovery for people with mood, anxiety, or psychotic disorders. Over 2,500 participants will receive either standard care or personalized medication advice based on their genetic profile. The goal is to see if this approach improves mental health recovery over 24 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pharmacogenetic testing
What this could lead to
If successful, this could make psychiatric medication more personalized, potentially improving recovery rates and reducing trial-and-error prescribing.
What could go wrong
This is a large but early-stage trial; genetic testing may not consistently improve outcomes, and results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety disorder bipolar disorder generalized anxiety disorder major depressive disorder mood disorder panic disorder psychotic disorder Psychotic Disorders schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DISORDERS MOOD DISORDERS PSYCHOTIC DISORDERS

Contacts and locations

Locations

  • Babeş-Bolyai University, Department of Clinical Psychology and Psychotherapy

    RECRUITING

    Cluj-Napoca, Romania

  • Fundació Clínic per a la Recerca Biomèdica, Department of Psychiatry and Psychology, Hospital Clínic

    RECRUITING

    Barcelona, Spain

  • King's College, Institute of Psychiatry, Psychology & Neuroscience

    RECRUITING

    London, United Kingdom

  • Ludwig-Maximilian University, University Hospital, Institute of Psychiatric Phenomics and Genomics (IPPG)

    RECRUITING

    München, Germany

  • Maastricht University, Department of Psychiatry and Neuropsychology

    RECRUITING

    Maastricht, Netherlands

  • Parnassia Psychiatric Institute, Department of Psychiatry

    RECRUITING

    Amsterdam, Netherlands

  • SUNY Upstate Medical University, Department of Psychiatry and Behavioural Sciences

    NOT_YET_RECRUITING

    Syracuse, New York, 13210, United States

  • University Hospital Bonn, Department of Psychiatry and Psychotherapy

    RECRUITING

    Bonn, Germany

  • University of Belgrade, Faculty of Pharmacy

    RECRUITING

    Belgrade, Serbia

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